Siem Reap Cruise Departures
Cruises that depart from Asia/Far East: Cambodia: Siem Reap
Cruises that visit Siem Reap
See all River Cruises that depart from Siem Reap
12 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Sep 23, Oct 7, Nov 4, Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, More...
10 Night - Deeper and Further On the Mekong River
Starting in Siem Reap to the Tonle Sap, The Tonle Sap Lake and Kampong Chhnang, Tonle Sap River, Peam Chi Korng Pottery Village, Koh Trong Island, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Disembark Saigon
2026 Sails: Oct 11, More...
12 Night - Fascinating Vietnam, Cambodia & the Mekong River (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, Nov 29, More...15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, Nov 29, More...
12 Night - Riches of the Mekong with Siem Reap Pre-Cruise and Ho Chi Minh City Post-Cruise
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, More...10 Night - Riches of the Mekong with Siem Reap Pre-Cruise
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, More...7 Night - Riches of the Mekong
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, Nov 29, Dec 13, Dec 27, More...9 Night - Riches of the Mekong with Ho Chi Minh Post-Cruise
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, More...
Cruises that depart from Asia/Far East: Cambodia: Siem Reap
Cruises that visit Siem Reap
See all River Cruises that depart from Siem Reap
Click on a cruise ship itinerary sailing from Siem Reap (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Siem Reap), please visit: Cruise Search or try our Virtual Cruise Advisor™.
12 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Sep 23, Oct 7, Nov 4, Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, More...
10 Night - Deeper and Further On the Mekong RiverStarting in Siem Reap to the Tonle Sap, The Tonle Sap Lake and Kampong Chhnang, Tonle Sap River, Peam Chi Korng Pottery Village, Koh Trong Island, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Disembark Saigon
2026 Sails: Oct 11, More...
12 Night - Fascinating Vietnam, Cambodia & the Mekong River (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, Nov 29, More...
15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2027 Sails: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, Nov 29, More...
12 Night - Riches of the Mekong with Siem Reap Pre-Cruise and Ho Chi Minh City Post-CruiseStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, More...
10 Night - Riches of the Mekong with Siem Reap Pre-CruiseStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, More...
7 Night - Riches of the MekongStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, Nov 29, Dec 13, Dec 27, More...
9 Night - Riches of the Mekong with Ho Chi Minh Post-CruiseStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2027 Sails: Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, More...
