Siem Reap River Cruise Departures
River Cruises that depart from Asia/Far East: Cambodia: Siem Reap
River Cruises that visit Siem Reap
See all Cruises that depart from Siem Reap
Tonle Sap Lake Cruises
River cruises by river name
7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Mar 22, Nov 11, More...3 Night - Phnom Penh and Siem Reap
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh Disembarkation
2026 Sails: Mar 22, More...
12 Night - Riches of the Mekong with Siem Reap Pre-Cruise and Ho Chi Minh City Post-Cruise
Starting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 27, Apr 10, Apr 24, 2027: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...10 Night - Riches of the Mekong with Siem Reap Pre-Cruise
Starting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 27, Apr 10, Apr 24, 2027: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...7 Night - Riches of the Mekong
Starting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 30, Apr 13, Apr 27, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12, Oct 26, Nov 9, Nov 23, Dec 7, 2027: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, Aug 16, Aug 30, Sep 13, More...9 Night - Riches of the Mekong with Ho Chi Minh Post-Cruise
Starting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 30, Apr 13, Apr 27, 2027: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, More...
12 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Prek KDam / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Apr 1, Apr 15, Apr 29, May 13, More...
12 Night - Treasures of the Mekong
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: May 9, Sep 19, Oct 3, Nov 28, 2027: Jan 2, Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...14 Night - Treasures of the Mekong Meandering Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Dec 15, More...12 Night - Temple Discovery and Meandering Along the Mekong Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...
River Cruises that depart from Asia/Far East: Cambodia: Siem Reap
River Cruises that visit Siem Reap
See all Cruises that depart from Siem Reap
Tonle Sap Lake Cruises
Click on a cruise ship itinerary sailing from Siem Reap (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Siem Reap), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Mar 22, Nov 11, More...
3 Night - Phnom Penh and Siem ReapStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh Disembarkation
2026 Sails: Mar 22, More...
12 Night - Riches of the Mekong with Siem Reap Pre-Cruise and Ho Chi Minh City Post-CruiseStarting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 27, Apr 10, Apr 24, 2027: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...
10 Night - Riches of the Mekong with Siem Reap Pre-CruiseStarting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 27, Apr 10, Apr 24, 2027: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...
7 Night - Riches of the MekongStarting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 30, Apr 13, Apr 27, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12, Oct 26, Nov 9, Nov 23, Dec 7, 2027: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, Aug 16, Aug 30, Sep 13, More...
9 Night - Riches of the Mekong with Ho Chi Minh Post-CruiseStarting in Siem Reap, Port Clarence, Atka, Phnom Penh, Tan Chau, Safford, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Mar 30, Apr 13, Apr 27, 2027: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, More...
12 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Prek KDam / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Apr 1, Apr 15, Apr 29, May 13, More...
12 Night - Treasures of the MekongStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: May 9, Sep 19, Oct 3, Nov 28, 2027: Jan 2, Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...
14 Night - Treasures of the Mekong Meandering CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Dec 15, More...
12 Night - Temple Discovery and Meandering Along the Mekong CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...
