Siem Reap River Cruise Departures
River Cruises that depart from Asia/Far East: Cambodia: Siem Reap
River Cruises that visit Siem Reap
See all Cruises that depart from Siem Reap
Tonle Sap Lake Cruises
River cruises by river name
7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Nov 14, Dec 26, 2027: Mar 6, Oct 30, Nov 13, Dec 26, 2028: Jan 9, Jan 23, Feb 6, Feb 20, Mar 5, Mar 19, Apr 2, Apr 16, More...
12 Night - Treasures of the Mekong
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Nov 14, Nov 28, 2027: Jan 30, Mar 13, Apr 10, Apr 24, May 8, Sep 18, Oct 2, More...
10 Night - Luxury Mekong and Temple Discovery Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Nov 14, Nov 28, 2027: Jan 30, Mar 13, Apr 10, Apr 24, May 8, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...
12 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, More...
7 Night - Riches of the Mekong
Starting in Siem Reap, Kampong Cham, Angkor Ban, Phnom Penh, Tan Chau, Sa Dec, Cai Be, My Tho Port, Ho Chi Minh City
2026 Sails: Nov 23, Dec 7, Dec 21, 2027: Jan 18, Feb 1, Mar 15, Mar 29, Apr 12, Apr 26, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, Dec 20, More...
14 Night - Treasures of the Mekong Meandering Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Dec 14, 2027: Jul 26, Aug 31, Nov 27, Dec 15, More...
12 Night - Temple Discovery and Meandering Along the Mekong Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...
10 Night - Deeper and Further On the Mekong River
Starting in Siem Reap to the Tonle Sap, The Tonle Sap Lake and Kampong Chang, Tonle Sap River, Peam Chi Korng Pottery Village, Koh Trong Island, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Disembark Saigon, Siem Reap / Steung Trang, Kratie / Dolphin Ground, Koh Trong, Steung Trang / Peam Chi Korng, Peam Chi Korng / Pak Russei Crafts, Oudong / Kampong Tralach, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Dec 23, 2027: Oct 10, Dec 23, More...
14 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Peam Chi Korng / Mekong Cruise, Angkor Ban / Phnom Penh, Phnom Penh, Phnom Penh / Cross Cambodia / Vietnam Border, Tan Chau, An Long / Gieng Island, My An Hung / Sa Dec, Ben Tre, Cho Gao canal / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2027 Sails: Jan 3, More...
12 Night - Sailing Vietnam and Cambodia's Mekong River
Starting in Siem Reap, Cambodia, Angkor, Steung Trang / Embark Ship, Angkor Ban / Prek Bang Kong, Kampong Tralach / Kampong Leaeng, Phnom Penh, Cruising the Mekong, Chau Doc, Vietnam, Binh Thanh Island / Cai Be, My Tho / Disembark Ship / Saigon (Ho Chi Minh City), Saigon
2027 Sails: Jan 13, Feb 24, 2028: Jan 12, Jan 26, Feb 23, Mar 8, More...
River Cruises that depart from Asia/Far East: Cambodia: Siem Reap
River Cruises that visit Siem Reap
See all Cruises that depart from Siem Reap
Tonle Sap Lake Cruises
Click on a cruise ship itinerary sailing from Siem Reap (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Siem Reap), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Nov 14, Dec 26, 2027: Mar 6, Oct 30, Nov 13, Dec 26, 2028: Jan 9, Jan 23, Feb 6, Feb 20, Mar 5, Mar 19, Apr 2, Apr 16, More...
12 Night - Treasures of the MekongStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Nov 14, Nov 28, 2027: Jan 30, Mar 13, Apr 10, Apr 24, May 8, Sep 18, Oct 2, More...
10 Night - Luxury Mekong and Temple Discovery CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Nov 14, Nov 28, 2027: Jan 30, Mar 13, Apr 10, Apr 24, May 8, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...
12 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, More...
7 Night - Riches of the MekongStarting in Siem Reap, Kampong Cham, Angkor Ban, Phnom Penh, Tan Chau, Sa Dec, Cai Be, My Tho Port, Ho Chi Minh City
2026 Sails: Nov 23, Dec 7, Dec 21, 2027: Jan 18, Feb 1, Mar 15, Mar 29, Apr 12, Apr 26, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, Dec 20, More...
14 Night - Treasures of the Mekong Meandering CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Dec 14, 2027: Jul 26, Aug 31, Nov 27, Dec 15, More...
12 Night - Temple Discovery and Meandering Along the Mekong CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...
10 Night - Deeper and Further On the Mekong RiverStarting in Siem Reap to the Tonle Sap, The Tonle Sap Lake and Kampong Chang, Tonle Sap River, Peam Chi Korng Pottery Village, Koh Trong Island, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Disembark Saigon, Siem Reap / Steung Trang, Kratie / Dolphin Ground, Koh Trong, Steung Trang / Peam Chi Korng, Peam Chi Korng / Pak Russei Crafts, Oudong / Kampong Tralach, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Dec 23, 2027: Oct 10, Dec 23, More...
14 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Peam Chi Korng / Mekong Cruise, Angkor Ban / Phnom Penh, Phnom Penh, Phnom Penh / Cross Cambodia / Vietnam Border, Tan Chau, An Long / Gieng Island, My An Hung / Sa Dec, Ben Tre, Cho Gao canal / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2027 Sails: Jan 3, More...
12 Night - Sailing Vietnam and Cambodia's Mekong RiverStarting in Siem Reap, Cambodia, Angkor, Steung Trang / Embark Ship, Angkor Ban / Prek Bang Kong, Kampong Tralach / Kampong Leaeng, Phnom Penh, Cruising the Mekong, Chau Doc, Vietnam, Binh Thanh Island / Cai Be, My Tho / Disembark Ship / Saigon (Ho Chi Minh City), Saigon
2027 Sails: Jan 13, Feb 24, 2028: Jan 12, Jan 26, Feb 23, Mar 8, More...