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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Musica
MSC Musica4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 26, Dec 6, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema4 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Ilhabela, Brazil, Itajai (Camboriu), Santos, Brazil
2026 Sails: Nov 29, Dec 6, Dec 13, 2027: Mar 21, More...
MSC Cruises, MSC Divina
MSC Divina4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 29, More...
MSC Cruises, MSC Musica
MSC Musica3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 30, Dec 3, 2027: Mar 5, Mar 12, Mar 19, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 2, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil
2026 Sails: Dec 5, 2027: Jan 2, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil
2026 Sails: Dec 5, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 5, Dec 12, Dec 19, 2027: Jan 2, Jan 9, Jan 16, Jan 30, Feb 6, Feb 13, Feb 20, Mar 6, Mar 13, Mar 20, Mar 27, More...
MSC Cruises, MSC Musica
MSC Musica3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 10, More...
MSC Cruises, MSC Musica
MSC Musica4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 13, 2027: Mar 22, More...

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Santos Cruise Departures