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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Costa Cruise Lines, Costa Diadema
Costa Diadema7 Night - South America Roundtrip from Santos
Starting in Santos / Sao Paulo, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil, Santos / Sao Paulo
2026 Sails: Dec 20, Dec 27, 2027: Jan 3, Jan 10, Jan 17, Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, More...
MSC Cruises, MSC Musica
MSC Musica2 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 20, More...
MSC Cruises, MSC Musica
MSC Musica6 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil
2026 Sails: Dec 20, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil, Itajai, Brazil
2026 Sails: Dec 20, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Dec 20, Dec 27, More...
MSC Cruises, MSC Divina
MSC Divina5 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Buzios, Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 21, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Copacabana (Rio de Janeiro), Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 26, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2027 Sails: Jan 10, More...
MSC Cruises, MSC Divina
MSC Divina3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2027 Sails: Jan 26, More...
MSC Cruises, MSC Divina
MSC Divina3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2027 Sails: Jan 29, Feb 12, Feb 19, Feb 22, Mar 1, Mar 8, More...

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Santos Cruise Departures