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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Seaview
MSC Seaview16 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Santa Cruz de Tenerife, Gibraltar, Alicante, Spain, Barcelona, Spain, Marseille (Provence), France
2026 Sails: Apr 11, More...
MSC Cruises, MSC Seaview
MSC Seaview17 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Santa Cruz de Tenerife, Gibraltar, Alicante, Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Apr 11, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Itajai, Brazil, Santos, Brazil
2026 Sails: Apr 16, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema22 Night - Transatlantic from Santos
Starting in Santos, Rio De Janeiro, Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon, Leixoes, Vigo, Le Havre, Southampton
2026 Sails: Apr 19, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema17 Night - Transatlantic from Santos
Starting in Santos, Rio De Janeiro, Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon
2026 Sails: Apr 19, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema26 Night - Transatlantic from Santos
Starting in Santos, Rio De Janeiro, Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon, Leixoes, Vigo, Le Havre, Southampton, Zeebrugge, Kiel
2026 Sails: Apr 19, More...
MSC Cruises, MSC Musica
MSC Musica4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 16, More...
MSC Cruises, MSC Musica
MSC Musica3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 20, Nov 23, Dec 17, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema2 Night - South America from Santos to Itajai
Starting in Santos, Brazil, Itajai (Camboriu)
2026 Sails: Nov 23, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Itajai (Camboriu), Santos, Brazil
2026 Sails: Nov 23, Nov 26, Dec 3, Dec 10, Dec 17, More...

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Santos Cruise Departures