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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Sinfonia
MSC Sinfonia Cruise Ship4 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Mar 13, More...
MSC Cruises, MSC Armonia
MSC Armonia Cruise Ship16 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Mindelo, Cape Verde, Las Palmas de Gran Canaria (Canary Islands), Spain, Tangier (Tetouan), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy
2026 Sails: Mar 15, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Mar 29, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises21 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil, Maceio, Brazil, Funchal (Madeira Islands), Portugal, Vigo (Santiago De Compostela), Spain, Gijon, Spain, Southampton (London), United Kingdom, Le Havre (Paris), France, Zeebrugge (Bruges), Belgium, Copenhagen, Denmark
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises1 Night - South America
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises4 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises12 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil, Maceio, Brazil, Funchal (Madeira Islands), Portugal
2026 Sails: Apr 2, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises15 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Santa Cruz de Tenerife, Gibraltar, Alicante, Spain, Barcelona, Spain
2026 Sails: Apr 11, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises16 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Santa Cruz de Tenerife, Gibraltar, Alicante, Spain, Barcelona, Spain, Marseille (Provence), France
2026 Sails: Apr 11, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises22 Night - Transatlantic from Santos
Starting in Santos, Rio De Janeiro, Salvador Bahia, Maceio, Praia, Santa Cruz de Tenerife, Casablanca, Cadice, Lisbon, Leixoes, Vigo, Le Havre, Southampton
2026 Sails: Apr 19, More...

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Santos Cruise Departures