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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Musica
MSC Musica4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 16, More...
MSC Cruises, MSC Musica
MSC Musica3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 20, Nov 23, Dec 17, 2027: Mar 29, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema2 Night - South America from Santos to Itajai
Starting in Santos, Brazil, Itajai, Brazil
2026 Sails: Nov 23, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Itajai, Brazil, Santos, Brazil
2026 Sails: Nov 26, Dec 3, Dec 10, Dec 17, More...
MSC Cruises, MSC Musica
MSC Musica4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 26, Dec 6, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema4 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Ilhabela, Brazil, Itajai, Brazil, Santos, Brazil
2026 Sails: Nov 29, Dec 6, Dec 13, 2027: Mar 21, More...
MSC Cruises, MSC Divina
MSC Divina4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 29, More...
MSC Cruises, MSC Seaview
MSC Seaview3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 29, More...
MSC Cruises, MSC Musica
MSC Musica3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Nov 30, Dec 3, Dec 10, 2027: Mar 19, More...
MSC Cruises, MSC Seaview
MSC Seaview3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 2, More...

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Santos Cruise Departures