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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Sinfonia
MSC Sinfonia Cruise Ship4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2025 Sails: Dec 1, 2026: Jan 26, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa Cruise Ship3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Portobelo, Brazil, Camboriu, Brazil, Santos, Brazil
2025 Sails: Dec 4, Dec 10, More...
MSC Cruises, MSC Seaview
MSC Seaview Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2025 Sails: Dec 6, Dec 19, 2026: Jan 3, Jan 31, Feb 14, Feb 21, Feb 28, Mar 14, Mar 28, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa Cruise Ship3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Camboriu, Brazil, Portobelo, Brazil, Santos, Brazil
2025 Sails: Dec 7, More...
MSC Cruises, MSC Preziosa
MSC Preziosa Cruises3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Angra Dos Reis, Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2025 Sails: Dec 7, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises3 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Itajai, Brazil, Santos, Brazil
2025 Sails: Dec 8, Dec 18, 2026: Apr 2, Apr 9, Apr 16, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia Cruise Ship3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2025 Sails: Dec 12, 2026: Feb 3, Feb 10, Feb 24, Mar 3, Mar 10, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa Cruise Ship3 Night - South America from Santos to Buenos Aires
Starting in Santos, Brazil, Buenos Aires, Argentina
2025 Sails: Dec 13, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema Cruises4 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Ilhabela, Brazil, Itajai, Brazil, Santos, Brazil
2025 Sails: Dec 14, 2026: Mar 29, Apr 5, Apr 12, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia Cruise Ship7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilhabela, Brazil, Ilha Grande, Brazil, Rio De Janeiro, Brazil, Buzios, Brazil, Itajai, Brazil, Santos (Sao Paulo), Brazil
2025 Sails: Dec 15, 2026: Jan 5, More...

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Santos Cruise Departures