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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Mar 21, Mar 28, Apr 4, More...
MSC Cruises, MSC Preziosa
MSC Preziosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Mar 22, More...
MSC Cruises, MSC Preziosa
MSC Preziosa4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Mar 29, More...
MSC Cruises, MSC Preziosa
MSC Preziosa5 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil, Maceio, Brazil
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa24 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil, Maceio, Brazil, Funchal (Madeira Islands), Portugal, Vigo (Santiago De Compostela), Spain, Gijon, Spain, Southampton (London), United Kingdom, Le Havre (Paris), France, Zeebrugge (Bruges), Belgium, Copenhagen, Denmark, Oslo, Norway, Hamburg, Germany
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa12 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil, Maceio, Brazil, Funchal (Madeira Islands), Portugal
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa1 Night - South America
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil
2026 Sails: Apr 2, More...
MSC Cruises, MSC Preziosa
MSC Preziosa4 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Ilheus, Brazil, Salvador, Brazil
2026 Sails: Apr 2, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema4 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Ilhabela, Brazil, Itajai, Brazil, Santos, Brazil
2026 Sails: Apr 5, More...
MSC Cruises, MSC Seaview
MSC Seaview15 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Santa Cruz de Tenerife, Gibraltar, Alicante, Spain, Barcelona, Spain
2026 Sails: Apr 11, More...

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Santos Cruise Departures