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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Sinfonia
MSC Sinfonia4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Jan 30, Feb 13, Feb 27, Mar 6, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 14, Mar 21, Mar 28, Apr 4, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema7 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil, Santos, Brazil
2026 Sails: Feb 1, Mar 1, Mar 22, More...
MSC Cruises, MSC Preziosa
MSC Preziosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Feb 1, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Feb 3, Feb 10, Feb 24, Mar 3, Mar 10, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Feb 6, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema7 Night - South America Roundtrip from Santos
Starting in Santos, Brazil, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil, Santos, Brazil
2026 Sails: Feb 8, More...
MSC Cruises, MSC Preziosa
MSC Preziosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Feb 8, Mar 1, Mar 8, Mar 15, Mar 22, More...
MSC Cruises, MSC Preziosa
MSC Preziosa7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Feb 15, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Feb 17, More...

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Santos Cruise Departures