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San Francisco Cruise Departures

Cruises that depart from North America: United States: California: San Francisco

Cruises that visit San Francisco

Click on a cruise ship itinerary sailing from San Francisco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Francisco), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Carnival Cruise Lines, Carnival Luminosa
Carnival Luminosa10 Night - Alaska Inside Passage & Glacier
Starting in San Francisco, Ca, Juneau, Ak, Skagway, Ak, Cruise Endicott Arm Fjord, Ketchikan, AK, Prince Rupert, Bc, Canada, San Francisco, Ca
2026 Sails: Sep 10, More...
Princess Cruises, Ruby Princess
Ruby Princess16 Night - Hawaiian Islands
Starting in San Francisco, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Kona, Hawaii, Kahului, Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Sep 17, More...
Princess Cruises, Ruby Princess
Ruby Princess10 Night - Mexican Riviera
Starting in San Francisco, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Oct 3, More...
Princess Cruises, Ruby Princess
Ruby Princess10 Night - Mexican Riviera Princess Players Invitational
Starting in San Francisco, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Oct 13, More...
Princess Cruises, Ruby Princess
Ruby Princess16 Night - Hawaiian Islands
Starting in San Francisco, California, Hilo, Hawaii, Kahului, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Oct 23, Nov 8, More...
Princess Cruises, Ruby Princess
Ruby Princess5 Night - West Coast Getaway with San Diego
Starting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2026 Sails: Nov 24, More...
Princess Cruises, Ruby Princess
Ruby Princess16 Night - Hawaiian Islands
Starting in San Francisco, California, Kahului, Hawaii, Hilo, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Nov 29, More...
Princess Cruises, Ruby Princess
Ruby Princess11 Night - Mexican Riviera Holiday
Starting in San Francisco, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Dec 15, More...
Princess Cruises, Ruby Princess
Ruby Princess16 Night - Hawaiian Islands
Starting in San Francisco, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Dec 26, 2027: Mar 16, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa51 Night - Round World from San Francisco
Starting in San Francisco, Honolulu, Hilo, Papeete, Suva, Lifou, Noumea, Sydney AU, Newcastle AU, New South Wales, Cairns, Rabaul, Tokyo, Kobe (Kyoto), Nagasaki, Pusan, Keelung, Taiwan, Hong Kong
2027 Sails: Jan 3, More...

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San Francisco Cruise Departures