Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
10 Night - Italy, France & Spain Cruise : Florence, Marseille & Barcelona
Starting in Rome (Civitavecchia), Portoferraio (Elba), Florence / Pisa (Livorno), Porto Venere, Portofino (Santa Margherita), Monte Carlo, Provence (Marseille), Sete, Palamos, Barcelona
2027 Sails: Jul 17, More...
10 Night - Mountains & Mystery
Starting in Rome (Civitavecchia), Salerno, Catania (Sicily), Valletta, Taranto, Igoumenitsa, Bari, Kotor, Dubrovnik, Croatia, Zadar, Trieste
2027 Sails: Jul 17, More...
7 Night - Cruise Roundtrip from Rome (Civitavecchia)
Starting in Rome (Civitavecchia), Bonifacio, Corsica, Amalfi, Positano, Capri, Sorrento, Rome (Civitavecchia)
2027 Sails: Jul 18, Oct 3, More...
9 Night - Trojan Trek Revisited
Starting in Rome (Civitavecchia), Salerno, Palermo (Sicily), Catania (Sicily), Zakynthos, Gythion, Mykonos, Volos, Canakkale (Troy), Istanbul
2027 Sails: Jul 19, More...19 Night - Rome, Ruins & Gondola Rides
Starting in Rome (Civitavecchia), Salerno, Palermo (Sicily), Catania (Sicily), Zakynthos, Gythion, Mykonos, Volos, Canakkale (Troy), Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Chania (Crete), Katakolon, Dubrovnik, Croatia, Korcula, Zadar, Ravenna, Venice (Fusina)
2027 Sails: Jul 19, More...
7 Night - Heaven On the Med
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Cruising the Ionian Sea, Kotor, Dubrovnik, Croatia, Rijeka, Venice (Trieste)
2027 Sails: Jul 22, Sep 9, More...14 Night - Harbors of Heritage
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Cruising the Ionian Sea, Kotor, Dubrovnik, Croatia, Rijeka, Venice (Trieste), Zadar, Bari, Argostoli (Cephalonia), Monemvasia, Santorini, Mykonos, Athens (Piraeus)
2027 Sails: Jul 22, More...7 Night - Cruise from Rome (Civitavecchia) to Valletta
Starting in Rome (Civitavecchia), Sorrento, Capri, Amalfi, Lipari, Aeolian Islands, Taormina (Mount Etna) Sicily, Syracuse IT, Sicily, Valletta
2027 Sails: Jul 25, More...
11 Night - Italy & Spain Solar Eclipse
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Portofino, Italy, Barcelona, Spain, Cartagena ES, Malaga, Spain, Cagliari, Sardinia, Italy, Sicily (Palermo), Italy, Rome (Civitavecchia), Italy
2027 Sails: Jul 26, More...9 Night - Italy & Greece Cruise : Amalfi, Crete & Santorini
Starting in Rome (Civitavecchia), Amalfi, Siracusa, Sicily, Argostoli, Gythion, Agios Nikolaos, (Crete), Rhodes, Marmaris, Santorini, Athens (Piraeus)
2027 Sails: Aug 6, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Deal link -> Special
10 Night - Italy, France & Spain Cruise : Florence, Marseille & BarcelonaStarting in Rome (Civitavecchia), Portoferraio (Elba), Florence / Pisa (Livorno), Porto Venere, Portofino (Santa Margherita), Monte Carlo, Provence (Marseille), Sete, Palamos, Barcelona
2027 Sails: Jul 17, More...
10 Night - Mountains & MysteryStarting in Rome (Civitavecchia), Salerno, Catania (Sicily), Valletta, Taranto, Igoumenitsa, Bari, Kotor, Dubrovnik, Croatia, Zadar, Trieste
2027 Sails: Jul 17, More...
7 Night - Cruise Roundtrip from Rome (Civitavecchia)Starting in Rome (Civitavecchia), Bonifacio, Corsica, Amalfi, Positano, Capri, Sorrento, Rome (Civitavecchia)
2027 Sails: Jul 18, Oct 3, More...
9 Night - Trojan Trek RevisitedStarting in Rome (Civitavecchia), Salerno, Palermo (Sicily), Catania (Sicily), Zakynthos, Gythion, Mykonos, Volos, Canakkale (Troy), Istanbul
2027 Sails: Jul 19, More...
19 Night - Rome, Ruins & Gondola RidesStarting in Rome (Civitavecchia), Salerno, Palermo (Sicily), Catania (Sicily), Zakynthos, Gythion, Mykonos, Volos, Canakkale (Troy), Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Chania (Crete), Katakolon, Dubrovnik, Croatia, Korcula, Zadar, Ravenna, Venice (Fusina)
2027 Sails: Jul 19, More...
7 Night - Heaven On the MedStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Cruising the Ionian Sea, Kotor, Dubrovnik, Croatia, Rijeka, Venice (Trieste)
2027 Sails: Jul 22, Sep 9, More...
14 Night - Harbors of HeritageStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Cruising the Ionian Sea, Kotor, Dubrovnik, Croatia, Rijeka, Venice (Trieste), Zadar, Bari, Argostoli (Cephalonia), Monemvasia, Santorini, Mykonos, Athens (Piraeus)
2027 Sails: Jul 22, More...
7 Night - Cruise from Rome (Civitavecchia) to VallettaStarting in Rome (Civitavecchia), Sorrento, Capri, Amalfi, Lipari, Aeolian Islands, Taormina (Mount Etna) Sicily, Syracuse IT, Sicily, Valletta
2027 Sails: Jul 25, More...
11 Night - Italy & Spain Solar EclipseStarting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Portofino, Italy, Barcelona, Spain, Cartagena ES, Malaga, Spain, Cagliari, Sardinia, Italy, Sicily (Palermo), Italy, Rome (Civitavecchia), Italy
2027 Sails: Jul 26, More...
Deal link -> Special
9 Night - Italy & Greece Cruise : Amalfi, Crete & SantoriniStarting in Rome (Civitavecchia), Amalfi, Siracusa, Sicily, Argostoli, Gythion, Agios Nikolaos, (Crete), Rhodes, Marmaris, Santorini, Athens (Piraeus)
2027 Sails: Aug 6, More...
