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Pennsylvania Cruise Departures

Cruises that depart from North America: United States: Pennsylvania

Cruises that visit Pennsylvania

See all River Cruises that depart from Pennsylvania

Click on a cruise ship itinerary sailing from Pennsylvania (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Pennsylvania), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Philadelphia : Pittsburgh


Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl7 Night - Bermuda-Philadelphia
Starting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Boston, Ma, Philadelphia, Pa
2027 Sails: May 13, More...
American Cruise Lines, American Liberty
American Liberty11 Night - American Revolution Cruise
Starting in Philadelphia, Pa, Day of Cruising, Annapolis, MD, St Michaels, MD, Day of Cruising, Norfolk, Va, Yorktown / Jamestown, VA, Williamsburg, VA, Mount Vernon, VA, Washington, DC
2027 Sails: Jul 12, More...
American Cruise Lines, American Melody
American Melody15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2027 Sails: Jul 16, More...
American Cruise Lines, American Symphony
American Symphony8 Night - Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2027 Sails: Jul 26, Aug 11, 2028: Jul 24, Aug 9, Aug 25, Sep 10, More...
American Cruise Lines, American Symphony
American Symphony15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2027 Sails: Aug 27, 2028: Sep 26, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl5 Night - Bermuda-Philadelphia
Starting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Philadelphia, Pa
2027 Sails: Sep 2, More...
Norwegian Line Tours, Norwegian Pearl Tours
Norwegian Pearl Tours13 Night - Pre Philadelphia Cruisetour
Starting in At Hotel, Philadelphia, Pa, Boston, Ma, Eastport, ME, Saint John NB (Bay of Fundy), Halifax, Canada, Sydney NS, Cape Breton Island, Canada, Charlottetown, Prince Edward Island, Canada, La Baie Saguenay River, Canada, Quebec City, Canada
2027 Sails: Sep 5, Sep 26, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl11 Night - Canada & New England - Philadelphia
Starting in Philadelphia, Pa, Boston, Ma, Eastport, ME, Saint John NB (Bay of Fundy), Halifax, Canada, Sydney NS, Cape Breton Island, Canada, Charlottetown, Prince Edward Island, Canada, La Baie Saguenay River, Canada, Quebec City, Canada
2027 Sails: Sep 7, Sep 28, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl11 Night - Canada & New England - Philadelphia
Starting in Philadelphia, Pa, Boston, Ma, Eastport, ME, Saint John NB (Bay of Fundy), Halifax, Canada, Sydney NS, Cape Breton Island, Canada, Charlottetown, Prince Edward Island, Canada, Portland ME, Philadelphia, Pa
2027 Sails: Oct 19, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl7 Night - Bermuda-Philadelphia
Starting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Philadelphia, Pa
2027 Sails: Oct 30, Nov 20, More...

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Pennsylvania Cruise Departures