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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Viking Ocean, Viking Sea
Viking Sea7 Night - Venice, the Adriatic & Greece
Starting in Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Chioggia)
2026 Sails: Sep 1, More...
Viking Ocean, Viking Vesta
Viking Vesta14 Night - Mediterranean & Italian Sojourn
Starting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Sep 1, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Italian Sojourn
Starting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Sep 1, More...
AmaWaterways Tours, AmaDahlia Tours
AmaDahlia Tours11 Night - Secrets of Egypt & the Nile with Cruise and Land Package : Cairo Pre-Cruise, Cruise Roundtrip Luxor, Cairo Post-Cruise
Starting in Cairo, Luxor, Edfu, Aswan, Keglsugl, Luxor, Qena, Luxor, Cairo
2026 Sails: Sep 2, Sep 9, Sep 16, Sep 23, Sep 30, Oct 7, Oct 14, Oct 21, Oct 28, Nov 4, Nov 11, Nov 18, Nov 25, Dec 2, Dec 9, More...
Windstar, Wind Surf
Wind Surf8 Night - Classic Italy & Dalmatian Coast
Starting in Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2026 Sails: Sep 2, More...
Windstar Tours, Wind Star Tours
Wind Star Tours10 Night - Delphi & Meteora : Grecian Treasures Cruise Tour
Starting in Athens, Greece, Delphi, Athens, Greece, Mykonos, Kusadasi, Patmos, Santorini, Monemvasia, Nafplio, Athens, Greece
2026 Sails: Sep 2, Sep 16, Sep 23, Oct 7, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona, Cagliari, Napoli, Civitavecchia (Rome)
2026 Sails: Sep 3, Sep 10, Sep 17, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, More...
Ritz-Carlton, Ilma
Ilma7 Night - Rome (Civitavecchia) / Venice
Starting in Rome (Civitavecchia), Gallipoli, Kotor, Korcula, Dubrovnik, Croatia, Zadar, Venice
2026 Sails: Sep 3, More...
Viking River Tours, Viking Ptah Tours
Viking Ptah Tours11 Night - Pharaohs & Pyramids
Starting in Cairo, Luxor, Qena, Luxor, Esna, Aswan, Kom Ombo, Edfu, Luxor, Cairo
2026 Sails: Sep 3, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, Nov 12, Nov 19, Nov 26, Dec 3, Dec 10, Dec 17, Dec 24, Dec 31, 2027: Jan 7, Jan 14, Jan 21, Jan 28, Feb 4, Feb 18, Feb 25, Mar 4, More...
Windstar, Wind Spirit
Wind Spirit7 Night - Treasures of the Greek Isles
Starting in Athens, Greece, Nafplio, Mykonos, Kusadasi, Patmos, Santorini, Monemvasia, Athens, Greece
2026 Sails: Sep 3, More...

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Mediterranean Cruise Departures