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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Silversea, Silver Ray
Silver Ray6 Night - Civitavecchia to Monte Carlo
Starting in Civitavecchia (Rome), Porto Santo Stefano, Livorno (Tuscany), Portofino, Toulon, Monte Carlo
2026 Sails: Aug 9, More...
Star Clippers, Star Clipper
Star Clipper11 Night - Greece, Montenegro, Croatia
Starting in Piraeus (Port of Athens), Greece, Mykonos, Greece, Santorini, Greece, Katakolon, Greece, Corfu, Greece, Kotor, Montenegro, Dubrovnik, Croatia, Korcula, Croatia, Hvar, Croatia, Cres, Croatia, Venice, Italy
2026 Sails: Aug 9, More...
Windstar, Wind Surf
Wind Surf9 Night - Adriatic Icons & Venetian Treasures
Starting in Venice, Rovinj, Zadar, Hvar, Kotor, Dubrovnik, Croatia, Piran, Venice
2026 Sails: Aug 9, More...
Queen Victoria14 Night - Western Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain, Ibiza, Spain, Cagliari, Sardinia, Italy, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy
2026 Sails: Aug 10, More...
Cunard Line, Queen Victoria
Queen Victoria7 Night - Western Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain
2026 Sails: Aug 10, More...
Cunard Line, Queen Victoria
Queen Victoria21 Night - Adriatic and Western Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain, Ibiza, Spain, Cagliari, Sardinia, Italy, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy
2026 Sails: Aug 10, More...
EXPLORA I14 Night - An Extended Journey Into Riviera Romance & Italian Marvels
Starting in Civitavecchia (Rome), Porto Santo Stefano (Argentario), Monte Carlo, Saint-Tropez, Tarragona, Palma De Mallorca, Barcelona, Cannes, Portofino, Livorno (Florence), Porto Cervo (Sardinia), Ajaccio (Corsica), Civitavecchia (Rome)
2026 Sails: Aug 10, More...
EXPLORA I7 Night - A Journey of Treasured Secrets & Chic Promenades
Starting in Civitavecchia (Rome), Porto Santo Stefano (Argentario), Monte Carlo, Saint-Tropez, Tarragona, Palma De Mallorca, Barcelona
2026 Sails: Aug 10, More...
EXPLORA II7 Night - A Journey from Venetian Elegance to Stunning Nature & Tranquil Harbour Hues
Starting in Fusina (Venice), Rovinj, Dubrovnik, Croatia, Brindisi, Fiskardo (Cephalonia), Milos, Piraeus (Athens)
2026 Sails: Aug 10, More...
EXPLORA II14 Night - An Extended Journey Through Golden Shores & Legendary Lands
Starting in Fusina (Venice), Rovinj, Dubrovnik, Croatia, Brindisi, Fiskardo (Cephalonia), Milos, Piraeus (Athens), Bari, Nydri, Lefkada, Pylos, Katapola, Mykonos, Piraeus (Athens)
2026 Sails: Aug 10, More...

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Mediterranean Cruise Departures