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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Celebrity Cruises, Celebrity Ascent
Celebrity Ascent10 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Olympia (Katakolon), Greece, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Montenegro, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 7, Sep 18, More...
Ritz-Carlton, Ilma
Ilma7 Night - Monte Carlo / Barcelona
Starting in Monte Carlo, Cannes, Saint-Tropez, Toulon, Mahon, Menorca, Balearic Islands, Palma de Mallorca, Mallorca, Balearic Islands, Barcelona
2026 Sails: Aug 7, More...
Sea Cloud, Sea Cloud II
Sea Cloud II10 Night - Concerts a La Carte
Starting in Piraeus, Poros, Milos / Cyclades, Fiskardo / Cephalonia / Ionian Islands, Kerkyra / Corfu / Ionian Islands, Otranto, Korcula, Split, Venice
2026 Sails: Aug 7, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa14 Night - Eastern Mediterranean from Marghera
Starting in Marghera (Venice), Bari, Thira (Santorini), Mykonos, Katakolon (Olympia), Marghera (Venice), Bari, Corfu, Zakynthos, Argostoli (Cephalonia), Dubrovnik, Croatia, Split, Marghera (Venice)
2026 Sails: Aug 8, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra7 Night - Athens to Istanbul Adventure
Starting in Athens (Piraeus), Greece, Milos, Greece, Santorini, Greece, Delos, Greece / Mykonos, Greece, Patmos, Greece, Kusadasi, Turkey, Kepez / Cruise the Dardanelles, Turkey, Istanbul, Turkey
2026 Sails: Aug 8, More...
Royal Caribbean, Explorer of the Seas
Explorer of the Seas7 Night - Greek Isles Cruise
Starting in Ravenna, Italy, Santorini, Greece, Mykonos, Greece, Athens (Piraeus), Greece, Split, Croatia, Ravenna, Italy
2026 Sails: Aug 8, Sep 5, More...
SeaDream Yacht Club, SeaDream I
SeaDream I11 Night - Yachting the Adriatic & Greek Isles Cruise
Starting in Venice, Piran, Hvar, Dubrovnik, Croatia, Kotor, Corfu, Syvota, Galaxidi (Delphi), Corinth Canal Transit, Tinos, Kythnos, Athens (Piraeus)
2026 Sails: Aug 8, More...
Star Clippers, Star Flyer
Star Flyer14 Night - Grand Voyage : Athens to Athens
Starting in Piraeus (Port of Athens), Greece, Rhodes, Greece, Bodrum, Turkey, Dalyan River, Turkey, Santorini, Greece, Hydra, Greece, Piraeus (Port of Athens), Greece, Dikili, Turkey, Myrina / Limnos, Greece, Skiathos, Greece, Skopelos, Greece, Poros, Greece, Piraeus (Port of Athens), Greece
2026 Sails: Aug 8, More...
Seabourn Quest7 Night - Greece & Dalmatian Delights
Starting in Dubrovnik, Croatia, Korcula, Croatia, Brindisi (Lecce), Italy, Sarande, Albania, Zakinthos, Greece, Nafplion, Greece, Piraeus (Athens), Greece
2026 Sails: Aug 9, Aug 23, Oct 4, More...
Seabourn Quest14 Night - Dalmatian Delights & Grecian Gems
Starting in Dubrovnik, Croatia, Korcula, Croatia, Brindisi (Lecce), Italy, Sarande, Albania, Zakinthos, Greece, Nafplion, Greece, Piraeus (Athens), Greece, Santorini, Greece, Monemvasia, Greece, Itea (Delphi), Greece, Nydri, Lefkada, Greece, Sarande, Albania, Dubrovnik, Croatia
2026 Sails: Aug 9, More...

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Mediterranean Cruise Departures