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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Norwegian Cruise Line, Norwegian Viva
Norwegian Viva9 Night - Europe - Classic Mediterranean
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Montenegro, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy, Livorno / Florence / Pisa, Italy, Nice / Monaco (Villefranche), France, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Aug 10, More...
Oceania Cruises, Oceania Nautica
Oceania Nautica20 Night - Adriatic & Iberia Discovery
Starting in Venice (Fusina), Pula / Rovinj, Dubrovnik, Croatia, Kotor, Igoumenitsa, Gallipoli, Messina (Sicily), Sorrento / Capri, Rome (Civitavecchia), Barcelona, Palma De Mallorca, Cartagena ES, Malaga, Casablanca, Seville (Cadiz), Portimao, Lisbon, Gijon, Spain, Bilbao
2026 Sails: Aug 10, More...
Oceania Cruises, Oceania Nautica
Oceania Nautica10 Night - Dalmatian & Italian Gems
Starting in Venice (Fusina), Pula / Rovinj, Dubrovnik, Croatia, Kotor, Igoumenitsa, Gallipoli, Messina (Sicily), Sorrento / Capri, Rome (Civitavecchia), Barcelona
2026 Sails: Aug 10, More...
Oceania Cruises, Oceania Regatta
Oceania Regatta7 Night - Adriatic Awakening
Starting in Athens (Piraeus), Chania (Crete), Argostoli (Cephalonia), Corfu, Sarande, Bari, Kotor, Dubrovnik, Croatia
2026 Sails: Aug 10, More...
Royal Caribbean, Brilliance of the Seas
Brilliance of the Seas7 Night - Italy, Croatia & the Adriatic
Starting in Trieste, Italy, Koper, Slovenia, Split, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Amalfi Coast (Salerno), Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 10, More...
Lindblad Expeditions, National Geographic Orion
National Geographic Orion7 Night - Croatia's Dalmatian Coast and Montenegro
Starting in Zadar, Croatia / Embark Ship, Sibenik / Krka National Park, Mljet National Park / Korcula, Kotor, Montenegro, Dubrovnik, Croatia, Komiza / Hvar, Zadar / Plitvice Lakes National Park, Zadar / Disembark Ship
2026 Sails: Aug 11, Aug 18, More...
Regent Seven Seas, Seven Seas Splendor
Seven Seas Splendor12 Night - Radiant Coasts
Starting in Athens (Piraeus), Cruising the Mediterranean Sea, Valletta, Naples / Pompeii, Rome (Civitavecchia), Tuscany (Livorno), Cannes, Barcelona, Cruising the Mediterranean Sea, Malaga, Portimao, Lisbon
2026 Sails: Aug 11, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Ancient Mediterranean Treasures
Starting in Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Aug 11, Dec 2, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona, Cagliari, Napoli, Civitavecchia (Rome)
2026 Sails: Aug 13, Aug 20, Aug 27, More...
MSC Cruises, MSC Fantasia
MSC Fantasia10 Night - Mediterranean
Starting in Piraeus (Athens), Greece, Kusadasi, Turkey, Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy, Katakolon (Olympia), Greece, Santorini, Greece, Piraeus (Athens), Greece
2026 Sails: Aug 13, More...

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Mediterranean Cruise Departures