Medellin River Cruise Departures
River Cruises that depart from South America: Colombia: Medellin
River Cruises that visit Medellin
See all Cruises that depart from Medellin
Magdalena River Cruises
River cruises by river name
10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: Mar 29, Apr 12, Apr 26, May 10, May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 25, Nov 8, Nov 22, Dec 6, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: Mar 29, Apr 12, Apr 26, May 10, May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 25, Nov 8, Nov 22, Dec 6, More...
10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: Apr 1, Apr 15, Apr 29, May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: Apr 1, Apr 15, Apr 29, May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 6, Apr 20, May 4, Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 6, Apr 20, May 4, Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Jan 17, Jan 31, Feb 14, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, San Felipe, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Jan 17, Jan 31, Feb 14, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, More...
River Cruises that depart from South America: Colombia: Medellin
River Cruises that visit Medellin
See all Cruises that depart from Medellin
Magdalena River Cruises
Click on a cruise ship itinerary sailing from Medellin (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Medellin), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: Mar 29, Apr 12, Apr 26, May 10, May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 25, Nov 8, Nov 22, Dec 6, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: Mar 29, Apr 12, Apr 26, May 10, May 24, Jun 7, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 25, Nov 8, Nov 22, Dec 6, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: Apr 1, Apr 15, Apr 29, May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: Apr 1, Apr 15, Apr 29, May 27, Jun 10, Jun 24, Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 6, Apr 20, May 4, Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 6, Apr 20, May 4, Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Jan 17, Jan 31, Feb 14, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, San Felipe, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Jan 17, Jan 31, Feb 14, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, More...
