Louisiana Cruise Departures

Cruises that depart from North America: United States: Louisiana

Cruises that visit Louisiana

See all River Cruises that depart from Louisiana

Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: New Orleans

Royal Caribbean International, Mariner of the Seas

7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Cozumel, Mexico, Puerto Costa Maya, Mexico, Belize City, Belize, New Orleans, Louisiana
2027 Sails: Dec 4, Dec 11, 2028: Jan 8, Jan 15, Jan 22, Feb 5, Feb 12, Feb 19, Mar 4, Mar 11, Mar 18, Mar 25, Apr 1, Apr 8, Apr 15, More...

Royal Caribbean International, Mariner of the Seas

7 Night - Western Caribbean Holiday
Starting in New Orleans, Louisiana, Cozumel, Mexico, Puerto Costa Maya, Mexico, Roatan, Honduras, New Orleans, Louisiana
2027 Sails: Dec 24, More...

Royal Caribbean International, Mariner of the Seas

8 Night - Western Caribbean Holiday
Starting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Cozumel, Mexico, George Town, Grand Cayman, New Orleans, Louisiana
2027 Sails: Dec 31, More...

Royal Caribbean International, Mariner of the Seas

7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, New Orleans, Louisiana
2028 Sails: Jan 29, More...

American Cruise Lines, American Serenade

7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2028 Sails: May 13, More...

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Louisiana Cruise Departures