Louisiana Cruise Departures

Cruises that depart from North America: United States: Louisiana

Cruises that visit Louisiana

See all River Cruises that depart from Louisiana

Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: New Orleans

7 Night - Western Caribbean Holiday
Starting in New Orleans, Louisiana, Cozumel, Mexico, Puerto Costa Maya, Mexico, Roatan, Honduras, New Orleans, Louisiana
2027 Sails: Dec 24, More...

Royal Caribbean, Mariner of the Seas

8 Night - Western Caribbean Holiday
Starting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Cozumel, Mexico, George Town, Grand Cayman, New Orleans, Louisiana
2027 Sails: Dec 31, More...

Royal Caribbean, Mariner of the Seas

7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, New Orleans, Louisiana
2028 Sails: Jan 29, More...

American Cruise Lines, American Symphony

15 Night - Mississippi & Cumberland Rivers Cruise
Starting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, Day of River Cruising, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Dover TN, Clarksville, TN, Nashville, TN
2028 Sails: Apr 9, More...

Viking River, Viking Mississippi

21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2028 Sails: Jul 11, More...

American Cruise Lines, American Symphony

7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2028 Sails: Nov 14, Nov 20, Nov 26, Dec 2, Dec 9, Dec 14, Dec 20, Dec 26, More...

Viking River, Viking Mississippi

7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2028 Sails: Dec 12, More...

Viking River, Viking Mississippi

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Louisiana Cruise Departures