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Los Angeles Cruise Departures

Cruises that depart from North America: United States: California: Los Angeles

Cruises that visit Los Angeles

Click on a cruise ship itinerary sailing from Los Angeles (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Los Angeles), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Cunard Line, Queen Anne
Queen Anne14 Night - Los Angeles to Miami
Starting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Apr 5, More...
Norwegian Cruise Line, Norwegian Bliss
Norwegian Bliss7 Night - Mexican Riviera - Los Angeles
Starting in Los Angeles, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 5, Apr 12, More...
Royal Caribbean, Navigator of the Seas
Navigator of the Seas4 Night - Catalina & Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Apr 6, More...
Princess Cruises, Emerald Princess
Emerald Princess10 Night - Baja Peninsula & Sea of Cortez
Starting in Los Angeles, California, Cabo San Lucas, Mexico, La Paz, Mexico, Loreto, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 9, More...
Royal Caribbean, Navigator of the Seas
Navigator of the Seas7 Night - Cabo, Vallarta & Mazatlan Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 10, More...
Royal Caribbean, Quantum of the Seas
Quantum of the Seas5 Night - Cabo Overnight Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Apr 10, More...
Virgin Voyages, Brilliant Lady
Brilliant Lady6 Night - California (and Mexico) Dreamin
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Apr 12, More...
Royal Caribbean, Quantum of the Seas
Quantum of the Seas6 Night - Cabo Overnight and Ensenada
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Apr 15, More...
Royal Caribbean, Navigator of the Seas
Navigator of the Seas7 Night - Cabo, Vallarta & Mazatlan
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 17, Apr 24, May 8, Jun 5, Jul 31, Aug 7, Aug 14, Aug 28, Sep 11, More...
Princess Cruises, Royal Princess
Royal Princess7 Night - Mexican Riviera
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 18, More...

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Los Angeles Cruise Departures