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Los Angeles Cruise Departures

Cruises that depart from North America: United States: California: Los Angeles

Cruises that visit Los Angeles

Click on a cruise ship itinerary sailing from Los Angeles (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Los Angeles), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Royal Caribbean, Quantum of the Seas
Quantum of the Seas4 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Sep 22, More...
Royal Caribbean, Ovation Of The Seas
Ovation Of The Seas4 Night - Catalina & Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Sep 24, More...
Princess Cruises, Grand Princess
Grand Princess10 Night - Baja Peninsula & Sea of Cortez
Starting in Los Angeles, California, Cabo San Lucas, Mexico, La Paz, Mexico, Loreto, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Sep 25, More...
Royal Caribbean, Quantum of the Seas
Quantum of the Seas25 Night - Transpacific Cruise
Starting in Los Angeles, California, Catalina Island, California, Kailua Kona, Hawaii, Honolulu, Oahu, Hawaii, Raiatea, French Polynesia, Papeete, Tahiti, Moorea, French Polynesia, International Dateline
2026 Sails: Sep 26, More...
Royal Caribbean, Ovation Of The Seas
Ovation Of The Seas3 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Sep 28, Oct 1, Oct 16, Nov 6, Nov 20, More...
Princess Cruises, Coral Princess
Coral Princess16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 29, More...
Windstar Tours, Star Breeze Tours
Star Breeze Tours10 Night - Dreams of Tahiti Air + Hotel Package from Lax
Starting in Los Angeles, Papeete, Moorea, Raiatea, Motu Mahaea, Near Tahaa, Bora Bora, Huahine, Papeete, Arrive in Papeete
2026 Sails: Sep 29, Oct 6, Oct 27, Nov 3, Dec 1, Dec 8, More...
Princess Cruises, Emerald Princess
Emerald Princess16 Night - Hawaiian Islands
Starting in Los Angeles, California, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Hilo, Hawaii, Kahului, Hawaii, Ensenada, Mexico, Los Angeles, California
2026 Sails: Sep 30, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit17 Night - Panama Canal Eastbound Cruise
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, Ocho Rios, Jamaica, George Town, Grand Cayman, Tampa, Florida
2026 Sails: Oct 1, More...
MSC Cruises, MSC Poesia
MSC Poesia15 Night - Msc Grand Voyages
Starting in Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Oct 2, More...

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Los Angeles Cruise Departures