Lake Como River Cruise Departures
River Cruises that depart from Mediterranean: Italy: Lake Como
River Cruises that visit Lake Como
See all Cruises that depart from Lake Como
River cruises by river name
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Mar 19, Apr 2, Apr 16, Apr 30, May 14, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Mar 31, Apr 28, May 12, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 15, Sep 29, Oct 13, Oct 27, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 8, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Sep 11, Oct 9, Oct 23, Nov 6, Nov 20, Dec 4, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 19, Oct 3, Oct 17, More...25 Night - Vineyards, Chateaux & Bordeaux with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation) Bordeaux (Embarkation), Bordeaux / Pauillac, Cussac Fort Medoc, Blaye / Bourg, Libourne Excursion to Saint-emilion, Bordeaux, Bordeaux Excursion to Arcachons Bay, Bordeaux (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Aug 28, Oct 9, More...18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Oct 9, Oct 23, Nov 6, More...10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Oct 24, Nov 7, 2027: Oct 23, Nov 6, More...10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Oct 31, Dec 26, 2027: Oct 30, Dec 25, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2027 Sails: Mar 26, Apr 9, Apr 23, May 7, Jul 16, Jul 30, More...
River Cruises that depart from Mediterranean: Italy: Lake Como
River Cruises that visit Lake Como
See all Cruises that depart from Lake Como
Click on a cruise ship itinerary sailing from Lake Como (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Lake Como), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Mar 19, Apr 2, Apr 16, Apr 30, May 14, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Mar 31, Apr 28, May 12, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 15, Sep 29, Oct 13, Oct 27, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 8, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Sep 11, Oct 9, Oct 23, Nov 6, Nov 20, Dec 4, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 19, Oct 3, Oct 17, More...
25 Night - Vineyards, Chateaux & Bordeaux with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation) Bordeaux (Embarkation), Bordeaux / Pauillac, Cussac Fort Medoc, Blaye / Bourg, Libourne Excursion to Saint-emilion, Bordeaux, Bordeaux Excursion to Arcachons Bay, Bordeaux (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Aug 28, Oct 9, More...
18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Oct 9, Oct 23, Nov 6, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Oct 24, Nov 7, 2027: Oct 23, Nov 6, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Oct 31, Dec 26, 2027: Oct 30, Dec 25, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2027 Sails: Mar 26, Apr 9, Apr 23, May 7, Jul 16, Jul 30, More...
