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Frankfurt Cruise Departures

Cruises that depart from Europe: Germany: Frankfurt

Cruises that visit Frankfurt

See all River Cruises that depart from Frankfurt

Click on a cruise ship itinerary sailing from Frankfurt (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Frankfurt), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Emerald Cruises, Emerald Astra
Emerald Astra Cruises7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Sep 1, Sep 8, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises10 Night - Legendary Rhine & Moselle & Romantic Franconia & Bavaria
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Nuremberg, Nuremberg / Munich, Munich / Neuschwanstein, Munich
2026 Sails: Sep 8, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Sep 15, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel
2026 Sails: Sep 15, More...
Uniworld Boutique River Cruise Collection, S.S. Elisabeth
S.S. Elisabeth Cruises7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Nov 25, Dec 9, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises11 Night - Christmastime from Frankfurt to Vienna
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Excursion to Munich (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways Cruise Tours, Avalon Tranquility II Cruise Tours
Avalon Tranquility II Cruises7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 6, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 14, More...

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Frankfurt Cruise Departures