Frankfurt Cruise Departures

Cruises that depart from Europe: Germany: Frankfurt

Cruises that visit Frankfurt

See all River Cruises that depart from Frankfurt

Click on a cruise ship itinerary sailing from Frankfurt (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Frankfurt), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Avalon Waterways Cruise Tours, Avalon Imagery II Cruise Tours

7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 14, More...

Uniworld Boutique River Cruise Collection, S.S. Emilie

7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Dec 15, More...

Avalon Waterways, Avalon Tranquility II

4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 16, More...

Avalon Waterways, Avalon Illumination

Emerald Cruises, Emerald Destiny

10 Night - Legendary Rhine & Moselle & Berlin
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt / Berlin, Berlin
2027 Sails: Jul 4, More...

Emerald Cruises, Emerald Sun

Scenic Luxury Cruises, Scenic Pearl

7 Night - Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel
2027 Sails: Aug 18, Oct 6, More...

Scenic Luxury Cruises, Scenic Pearl

7 Night - Charming Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Zurich
2027 Sails: Aug 18, Oct 6, More...

Scenic Luxury Cruises, Scenic Pearl

11 Night - Charming Castles & Vineyards of the Rhine & Moselle with Switzerland
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Montreux, Montreux, Montreux / Bern, Bern / Lucerne / Zurich, Zurich
2027 Sails: Aug 18, More...

Emerald Cruises, Emerald Sun

10 Night - Legendary Rhine & Moselle & Romantic Franconia & Bavaria
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Nuremberg, Nuremberg / Munich, Munich / Neuschwanstein, Munich
2027 Sails: Aug 30, More...

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Frankfurt Cruise Departures