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Frankfurt Cruise Departures

Cruises that depart from Europe: Germany: Frankfurt

Cruises that visit Frankfurt

See all River Cruises that depart from Frankfurt

Click on a cruise ship itinerary sailing from Frankfurt (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Frankfurt), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Emerald Cruises, Emerald Destiny
Emerald Destiny7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Aug 24, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Heidelberg, Rastatt (Baden-Baden), Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Aug 31, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Heidelberg, Rastatt (Baden-Baden), Strasbourg, Breisach / Colmar, Basel
2026 Sails: Aug 31, More...
Emerald Cruises, Emerald Astra
Emerald Astra7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Sep 1, Sep 8, More...
Emerald Cruises, Emerald Astra
Emerald Astra7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Heidelberg, Rastatt (Baden-Baden), Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Sep 15, More...
Emerald Cruises, Emerald Astra
Emerald Astra7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Heidelberg, Rastatt (Baden-Baden), Strasbourg, Breisach / Colmar, Basel
2026 Sails: Sep 15, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby7 Night - Charming Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Zurich
2026 Sails: Oct 7, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby7 Night - Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel
2026 Sails: Oct 7, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II11 Night - Christmastime from Frankfurt to Vienna
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Excursion to Munich (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 6, More...

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Frankfurt Cruise Departures