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Frankfurt Cruise Departures

Cruises that depart from Europe: Germany: Frankfurt

Cruises that visit Frankfurt

See all River Cruises that depart from Frankfurt

Click on a cruise ship itinerary sailing from Frankfurt (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Frankfurt), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Emerald Cruises, Emerald Sun
Emerald Sun7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Heidelberg, Rastatt (Baden-Baden), Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Jul 11, More...
Emerald Cruises, Emerald Sun
Emerald Sun7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Heidelberg, Rastatt (Baden-Baden), Strasbourg, Breisach / Colmar, Basel
2026 Sails: Jul 11, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby7 Night - Charming Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Zurich
2026 Sails: Aug 5, Oct 7, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby11 Night - Charming Castles & Vineyards of the Rhine & Moselle with Switzerland
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Montreux, Montreux, Montreux / Bern, Bern / Lucerne / Zurich, Zurich
2026 Sails: Aug 5, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby7 Night - Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel
2026 Sails: Aug 5, Oct 7, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Aug 17, Aug 24, More...
Emerald Cruises, Emerald Astra
Emerald Astra7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Sep 1, Sep 8, More...
Uniworld, S.S. Elisabeth
S.S. Elisabeth7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Nov 25, Dec 9, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 6, More...

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Frankfurt Cruise Departures