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Frankfurt Cruise Departures

Cruises that depart from Europe: Germany: Frankfurt

Cruises that visit Frankfurt

See all River Cruises that depart from Frankfurt

Click on a cruise ship itinerary sailing from Frankfurt (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Frankfurt), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Uniworld Boutique River Cruise Collection, River Duchess
River Duchess Cruise Ship7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2025 Sails: Nov 24, Dec 8, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2025 Sails: Dec 5, 2026: Dec 14, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises12 Night - Christmastime from Frankfurt to Budapest
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Excursion to Munich / Nuremberg (Embarkation), Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2025 Sails: Dec 5, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises7 Night - Charming Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Zurich
2026 Sails: Apr 22, Jul 1, Aug 5, Oct 7, 2027: May 5, Jul 21, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises11 Night - Charming Castles & Vineyards of the Rhine & Moselle with Switzerland
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Montreux, Montreux, Montreux / Bern, Bern / Lucerne / Zurich, Zurich
2026 Sails: Apr 22, Jul 1, Aug 5, 2027: May 5, Jul 21, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Jun 27, Jul 4, 2027: Aug 2, Aug 9, Aug 30, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises7 Night - Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel
2026 Sails: Jul 1, Aug 5, Oct 7, 2027: May 5, Jul 21, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Jul 11, 2027: Aug 16, Sep 6, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel
2026 Sails: Jul 11, 2027: Aug 16, Sep 6, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises10 Night - The Majestic Rhine & Lucerne - Zurich
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Lucerne, Lucerne, Lucerne / Zurich, Zurich
2026 Sails: Jul 11, More...

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Frankfurt Cruise Departures