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Frankfurt River Cruise Departures

River Cruises that depart from Europe: Germany: Frankfurt

River Cruises that visit Frankfurt

See all Cruises that depart from Frankfurt

Main River Cruises

Click on a cruise ship itinerary sailing from Frankfurt (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Frankfurt), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name


Scenic Luxury, Scenic Ruby
Scenic Ruby7 Night - Charming Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Zurich
2026 Sails: Aug 5, Oct 7, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby11 Night - Charming Castles & Vineyards of the Rhine & Moselle with Switzerland
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Montreux, Montreux, Montreux / Bern, Bern / Lucerne / Zurich, Zurich
2026 Sails: Aug 5, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby7 Night - Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel
2026 Sails: Aug 5, Oct 7, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Aug 17, Aug 24, More...
Emerald Cruises, Emerald Astra
Emerald Astra7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz, Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz / Frankfurt
2026 Sails: Sep 1, Sep 8, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways Tours, Avalon Tranquility II Tours
Avalon Tranquility II Tours7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 6, More...
Uniworld, S.S. Elisabeth
S.S. Elisabeth7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Dec 9, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 14, More...
Avalon Waterways Tours, Avalon Imagery II Tours
Avalon Imagery II Tours7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 14, More...

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Frankfurt River Cruise Departures