Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Royal Caribbean, Explorer of the Seas

5 Night - Eastern Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Grand Turk, Turks and Caicos, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Nov 13, More...

Royal Caribbean, Oasis of the Seas

3 Night - Bahamas & Perfect Day Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Nov 13, Nov 20, Nov 27, Dec 4, Dec 11, Dec 18, 2027: Jan 8, Jan 15, Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Apr 16, Nov 19, Dec 3, Dec 17, Dec 31, More...

American Cruise Lines, American Legend

8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 9, Feb 23, Nov 25, Dec 9, Dec 23, More...

Carnival Cruise Lines, Carnival Magic

8 Night - Southern Caribbean
Starting in Miami, Fl, Celebration Key, the Bahamas, Aruba, Curacao, Miami, Fl
2026 Sails: Nov 14, 2027: Jan 9, Feb 6, Mar 20, Apr 3, More...

Celebrity Cruises, Celebrity Apex

Deal link -> Special

7 Night - Bahamas, Mexico & Cayman
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, George Town, Grand Cayman, Cozumel, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Nov 14, More...

Holland America, Eurodam

Deal link -> Special

7 Night - Western Caribbean : Greater Antilles & Mexico
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Nov 14, Dec 5, More...

Holland America, Eurodam

14 Night - Western & Eastern Caribbean : Mexico & Bahamas
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Key West, Florida, Fort Lauderdale, Florida
2026 Sails: Nov 14, More...

Margaritaville at Sea, Margaritaville Islander

6 Night - Belize & Progreso
Starting in Port Tampa Bay, Belize, Progreso, Mexico, Port Tampa Bay
2026 Sails: Nov 14, More...

MSC Cruises, MSC Grandiosa

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Cozumel, Mexico, Costa Maya, Mexico, Port Canaveral (Orlando), Florida
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, More...

MSC Cruises, MSC Grandiosa

14 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Cozumel, Mexico, Costa Maya, Mexico, Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, More...

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