Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Charlotte Amalie (St Thomas) Virgin Islands, Basseterre, St Kitts and Nevis, Philipsburg, St Maarten, St Johns AG, Antigua, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2026 Sails: Nov 12, More...

Norwegian Cruise Line, Norwegian Prima

3 Night - Eastern Caribbean - Port Canaveral
Starting in Orlando Beaches / Port Canaveral, Fl, Puerto Plata, Dominican Republic, San Juan, Pr
2026 Sails: Nov 12, More...

Royal Caribbean, Jewel of the Seas

4 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Tampa, Florida
2026 Sails: Nov 12, Dec 16, 2027: Jan 7, Jan 21, Feb 4, Feb 18, Mar 4, Mar 18, Apr 1, Apr 15, More...

American Cruise Lines, American Pioneer

8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Nov 13, Nov 20, Nov 27, Dec 4, Dec 11, Dec 18, Dec 25, 2027: Jan 1, Jan 8, Jan 15, Jan 22, Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Apr 16, Apr 23, More...

Celebrity Cruises, Celebrity Ascent

Deal link -> Special

10 Night - Ultimate Southern Caribbean
Starting in Fort Lauderdale, Florida, Philipsburg, St Maarten, Castries, St Lucia, St Georges, Grenada, Bridgetown, Barbados, St Johns AG, Antigua, Fort Lauderdale, Florida
2026 Sails: Nov 13, Dec 4, Dec 14, 2027: Jan 15, Feb 26, Mar 19, Apr 9, More...

Norwegian Cruise Line, Norwegian Escape

7 Night - Eastern Caribbean - Port Canaveral
Starting in Orlando Beaches / Port Canaveral, Fl, Puerto Plata, Dominican Republic, St Thomas, Vi, Tortola, British Virgin Islands, Great Stirrup Cay, Bahamas, Orlando Beaches / Port Canaveral, Fl
2026 Sails: Nov 13, Nov 20, Nov 27, Dec 4, Dec 11, Dec 23, Dec 30, 2027: Jan 15, Jan 22, Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, More...

Norwegian Line Tours, Norwegian Epic Tours

9 Night - Space Discovery Cruisetour
Starting in At Hotel, Orlando Beaches / Port Canaveral, Fl, Great Stirrup Cay, Bahamas, Ocho Rios, Jamaica, Cozumel, Mexico, Orlando Beaches / Port Canaveral, Fl
2026 Sails: Nov 13, More...

Ritz-Carlton, Ilma

3 Night - Miami, Florida / Miami, Florida
Starting in Miami, Florida, Bimini, Sandy Point (Marina Day), Miami, Florida
2026 Sails: Nov 13, 2027: Mar 22, Mar 25, More...

Royal Caribbean, Explorer of the Seas

5 Night - Eastern Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Grand Turk, Turks and Caicos, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Nov 13, More...

Royal Caribbean, Oasis of the Seas

3 Night - Bahamas & Perfect Day Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Nov 13, Nov 20, Nov 27, Dec 4, Dec 11, Dec 18, 2027: Jan 8, Jan 15, Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Apr 16, Nov 19, Dec 3, Dec 17, Dec 31, More...

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