Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Princess Cruises, Majestic Princess

8 Night - Eastern Caribbean with St. Thomas
Starting in Fort Lauderdale, Florida, Amber Cove, Dominican Republic, San Juan, Puerto Rico, St Maarten, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Jan 3, Feb 14, More...

Regent Seven Seas Cruises, Seven Seas Grandeur

22 Night - Tropical Escape Across the Canal
Starting in Miami, Cruising the Florida Straits, George Town, Ocho Rios, Jamaica, Cruising the Caribbean Sea, Bonaire (Kralendijk), Willemstad AN, Oranjestad, Cartagena CO, Cruising the Caribbean Sea, Puerto Limon, Panama Canal Transit, Panama City, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Vallarta, Cabo San Lucas, Cruising the Pacific Ocean, Ensenada, Los Angeles
2026 Sails: Jan 3, More...

Regent Seven Seas Cruises, Seven Seas Mariner

7 Night - Lush Islands, Lovely Shores
Starting in Miami, Cruising the Florida Straits, Cozumel, Mexico, Roatan, Harvest Caye, Costa Maya, Mexico, Cruising the Florida Straits, Miami
2026 Sails: Jan 3, More...

Royal Caribbean International (RCL), RCL Adventure of the Seas

6 Night - Western Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, George Town, Grand Cayman, Falmouth, Jamaica, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Jan 3, Feb 14, Mar 14, Apr 11, More...

Royal Caribbean International (RCL), RCL Allure of the Seas

8 Night - Eastern Caribbean & Perfect Day
Starting in Fort Lauderdale, Florida, Charlotte Amalie, St Thomas, Philipsburg, St Maarten, San Juan, Puerto Rico, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 3, Jan 31, Feb 28, More...

Royal Caribbean International (RCL), RCL Enchantment of the Seas

5 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Cozumel, Mexico, Tampa, Florida
2026 Sails: Jan 3, Jan 12, Jan 17, Jan 26, Jan 31, Feb 9, Feb 14, Feb 23, Feb 28, Mar 9, Mar 14, Mar 23, Mar 28, Apr 6, Apr 11, Apr 20, More...

Royal Caribbean International (RCL), RCL Grandeur of the Seas

7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Roatan, Honduras, Belize City, Belize, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Jan 3, Feb 14, Mar 28, More...

Royal Caribbean International (RCL), RCL Icon of the Seas

7 Night - Eastern Caribbean & Perfect Day
Starting in Miami, Florida, Philipsburg, St Maarten, Charlotte Amalie, St Thomas, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Jan 3, Jan 17, Jan 31, Feb 14, Feb 28, Mar 14, Mar 28, Apr 11, Apr 25, May 16, May 30, Jun 27, Jul 11, Aug 1, Aug 8, Aug 22, Sep 12, Sep 19, Oct 3, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...

Royal Caribbean International (RCL), RCL Rhapsody of the Seas

7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Puerto Costa Maya, Mexico, Roatan, Honduras, Tampa, Florida
2026 Sails: Jan 3, Jan 31, Mar 28, More...

Virgin Voyages, Resilient Lady

7 Night - Cozumel, Grand Cayman & Bimini
Starting in Miami, George Town, Cayman Islands, Cozumel (Playa Del Carmen), Mexico, The Beach Club at Bimini, Bahamas, Miami
2026 Sails: Jan 3, More...

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