Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Holland America, Zuiderdam

14 Night - Western & Eastern Caribbean : Mexico & Bahamas
Starting in Miami, Florida, Key West, Florida, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Miami, Florida, RelaxAway, Half Moon Cay, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Nassau, Bahamas, Miami, Florida
2026 Sails: Nov 21, More...

Holland America, Zuiderdam

7 Night - Western Caribbean : Greater Antilles & Mexico
Starting in Miami, Florida, Key West, Florida, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Miami, Florida
2026 Sails: Nov 21, More...

MSC Cruises, MSC Grandiosa

14 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Cozumel, Mexico, Costa Maya, Mexico, Port Canaveral (Orlando), Florida
2026 Sails: Nov 21, Dec 5, Dec 19, 2027: Jan 2, Jan 16, Jan 30, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, More...

MSC Cruises, MSC Grandiosa

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida
2026 Sails: Nov 21, Dec 5, Dec 19, 2027: Jan 2, Jan 16, Jan 30, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, More...

MSC Cruises, MSC Meraviglia

8 Night - Caribbean and Antilles
Starting in Miami, Florida, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, Charlotte Amalie (St Thomas) Virgin Islands, Amber Cove, Dominican Republic, Miami, Florida
2026 Sails: Nov 21, Dec 19, 2027: Jan 2, Feb 13, Mar 27, More...

MSC Cruises, MSC Meraviglia

14 Night - Caribbean and Antilles
Starting in Miami, Florida, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, Charlotte Amalie (St Thomas) Virgin Islands, Amber Cove, Dominican Republic, Miami, Florida, Grand Turk Island, Turks and Caicos, Ocean Cay Msc Marine Reserve, Bahamas, Nassau, Bahamas, Miami, Florida
2026 Sails: Nov 21, Dec 19, 2027: Jan 2, Mar 27, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Western Caribbean - Tampa
Starting in Tampa, Fl, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Tampa, Fl
2026 Sails: Nov 21, More...

Princess Cruises, Star Princess

14 Night - Eastern / Western Caribbean Adventurer with Celebration Key
Starting in Fort Lauderdale, Florida, Roatan (Isla Tropicale), Honduras, Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Celebration Key, Bahamas, Fort Lauderdale, Florida
2026 Sails: Nov 21, 2027: Jan 30, More...

Royal Caribbean, Adventure of the Seas

8 Night - Southern Caribbean Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Cabo Rojo, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Fort Lauderdale, Florida
2026 Sails: Nov 21, 2027: Jan 16, Feb 13, Mar 13, Mar 27, Apr 10, More...

Royal Caribbean, Harmony of the Seas

7 Night - Eastern Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Orlando (Port Canaveral), Fl
2026 Sails: Nov 21, More...

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