Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

American Cruise Lines, American Maverick

15 Night - Grand Florida Coast & Keys Cruise
Starting in Amelia Island, FL, Day of Cruising, Green Cove Springs, FL, St Augustine, FL, Cruising the Tolomato River, Cape Canaveral, FL, Day of Cruising, West Palm Beach, FL, Key Biscayne, FL, Key West, FL, Day of Cruising, Marco Island, FL, Punta Gorda, FL, St Petersburg FL
2026 Sails: Oct 20, 2027: Nov 7, 2028: Nov 20, More...

Princess Cruises, Star Princess

4 Night - Caribbean Getaway with Grand Turk
Starting in Fort Lauderdale, Florida, Grand Turk, Turks and Caicos, Fort Lauderdale, Florida
2026 Sails: Oct 20, More...

Viking Ocean, Viking Mars

14 Night - Panama Canal & Central America
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Oct 20, Nov 23, 2028: Nov 14, 2029: Jan 7, Jan 21, Feb 4, Feb 18, More...

MSC Cruises, MSC Poesia

10 Night - Caribbean and Antilles
Starting in Miami, Florida, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, Miami, Florida
2026 Sails: Oct 22, 2027: Oct 21, Dec 2, More...

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2026 Sails: Oct 22, 2027: Oct 21, Dec 2, More...

Royal Caribbean, Freedom of the Seas

9 Night - Southern Caribbean Cruise
Starting in Miami, Florida, Nassau, Bahamas, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, Miami, Florida
2026 Sails: Oct 22, More...

Royal Caribbean, Jewel of the Seas

3 Night - Bahamas Getaway Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 22, More...

Virgin Voyages, Resilient Lady

4 Night - Key West & Bimini Beach Club
Starting in Miami, Key West, The Beach Club at Bimini, Bahamas, Miami
2026 Sails: Oct 22, More...

Celebrity Cruises, Celebrity Reflection

9 Night - Aruba, Bonaire & Curacao Cruise
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Fort Lauderdale, Florida
2026 Sails: Oct 24, More...

Holland America, Eurodam

7 Night - Eastern Caribbean : Amber Cove & Key West
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Key West, Florida, Fort Lauderdale, Florida
2026 Sails: Oct 24, More...

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