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Cartagena CO Cruise Departures

Cruises that depart from South America: Colombia: Cartagena CO

Cruises that visit Cartagena CO

See all River Cruises that depart from Cartagena CO

Click on a cruise ship itinerary sailing from Cartagena CO (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cartagena CO), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Cartagena CO
Shore Excursions

AmaWaterways, AmaMelodia
AmaMelodia Cruises7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Mar 11, Mar 25, Apr 8, May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2026 Sails: Mar 15, Apr 12, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama, Cartagena CO
2026 Sails: Mar 29, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship6 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2026 Sails: Apr 19, More...
Royal Caribbean International, Grandeur of the Seas
Grandeur of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, More...
Royal Caribbean International, Grandeur of the Seas
Grandeur of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Sep 6, More...
Lindblad Expeditions, National Geographic Quest
National Geographic Quest Cruises7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Gatun Lake, Panama City, Panama / Disembark Ship
2026 Sails: Nov 7, More...
Royal Caribbean International, Grandeur of the Seas
Grandeur of the Seas Cruise Ship6 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2026 Sails: Nov 8, 2027: Apr 18, More...
Crystal, Crystal Serenity
Crystal Serenity Cruise Ship10 Night - The Americas & Caribbean
Starting in Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City), Puerto Caldera
2026 Sails: Dec 2, More...
Royal Caribbean International, Grandeur of the Seas
Grandeur of the Seas Cruise Ship7 Night - Southern Caribbean Holiday
Starting in Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama, Cartagena CO
2026 Sails: Dec 20, More...

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Cartagena CO Cruise Departures