US East Coast Cruises

River Cruises sailing on the US East Coast

Click on a cruise ship itinerary sailing on the US East Coast (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just US East Coast), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the US East Coast also sail: Beaufort River : Hudson River : Patapsco River : Potomac River : Severn River : Tennessee River : Tolomato River : US South Coast

7 Night - Hudson River Fall Foliage Cruises
Starting in New York, NY, Sleepy Hollow, NY, West Point, NY, Kingston, NY / Hyde Park, NY, Catskill, NY, Day of Cruising, Albany NY
2026 Sails: Oct 2, Oct 16, 2027: Sep 26, Oct 10, Oct 24, 2028: Sep 30, Oct 14, Oct 28, More...

American Cruise Lines, American Patriot

15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2026 Sails: Oct 2, 2028: Oct 6, More...

American Cruise Lines, American Liberty

7 Night - Hudson River Fall Foliage Cruises
Starting in Albany NY, Catskill, NY, Kingston, NY / Hyde Park, NY, Day of Cruising, West Point, NY, Sleepy Hollow, NY, New York, NY
2026 Sails: Oct 4, Oct 18, More...

American Cruise Lines, American Legend

American Cruise Lines, American Maverick

7 Night - Yankee Seaports Cruise
Starting in Boston, Ma, Plymouth, MA, Newport, Ri, New London / Mystic, CT, Sag Harbor, NY, Old Saybrook, CT, New York, NY
2026 Sails: Oct 9, 2027: Oct 26, More...

American Cruise Lines, American Pioneer

7 Night - Yankee Seaports Cruise
Starting in Boston, Ma, Plymouth, MA, Newport, Ri, New London / Mystic, CT, Sag Harbor, NY, Old Saybrook, CT, New York, NY
2026 Sails: Oct 18, 2027: Oct 23, More...

American Cruise Lines, American Maverick

15 Night - Grand Florida Coast & Keys Cruise
Starting in Amelia Island, FL, Day of Cruising, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Day of Cruising, Port Canaveral, FL, West Palm Beach, FL, Key Biscayne, FL, Key West, FL, Day of Cruising, Marco Island, FL, Punta Gorda, FL, St Petersburg FL
2026 Sails: Oct 20, 2027: Feb 16, Nov 7, 2028: Nov 20, More...

American Cruise Lines, American Liberty

14 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 27, More...

American Cruise Lines, American Patriot

10 Night - American Revolution Cruise
Starting in Washington, DC, Annapolis, MD, St Michaels, MD, Day of Cruising, Norfolk, Va, Williamsburg / Yorktown, VA, Mount Vernon, VA, Washington, DC
2026 Sails: Oct 29, Nov 8, 2028: Apr 25, May 5, May 15, Oct 29, More...

American Cruise Lines, American Maverick

8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Nov 3, Nov 10, Nov 17, Nov 24, Dec 1, Dec 8, Dec 15, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Jan 19, Jan 26, Mar 2, Mar 9, Mar 16, Mar 23, Mar 30, Apr 6, Apr 13, Nov 21, Nov 28, Dec 5, Dec 12, More...

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