US East Coast Cruises
River Cruises sailing on the US East Coast
River cruises by river name
Cruises on the US East Coast also sail:
Beaufort River : Hudson River : Patapsco River : Potomac River : Severn River : St Johns River : Tennessee River : Tolomato River : US South Coast
15 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 26, More...
15 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 31, 2027: Nov 8, More...
8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Nov 3, Nov 10, Nov 17, Nov 24, Dec 1, Dec 8, Dec 15, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Jan 19, Jan 26, Feb 2, Feb 9, Feb 16, Feb 23, Mar 2, Mar 9, Mar 16, Mar 23, Mar 30, Apr 6, Apr 13, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 7, 2027: Mar 19, Apr 2, Apr 16, Apr 30, Nov 8, 2028: Feb 4, Feb 18, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Nov 13, More...8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 9, Feb 23, Nov 25, Dec 9, Dec 23, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Nov 21, Dec 5, Dec 19, 2027: Feb 3, Feb 17, Mar 3, Mar 17, Nov 29, Dec 13, Dec 27, 2028: Feb 16, Mar 1, Dec 2, Dec 16, Dec 30, More...15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, 2028: Mar 8, More...11 Night - American Revolution Cruise
Starting in Washington, DC, Day of Cruising Chesapeake Bay, Norfolk, Va, Day of Cruising, Yorktown / Jamestown, VA, Williamsburg, VA, St Michaels, MD, Annapolis, MD, Day of Cruising Chesapeake Bay and the Delaware River, Philadelphia, Pa
2027 Sails: Apr 7, Apr 27, May 17, More...11 Night - American Revolution Cruise
Starting in Philadelphia, Pa, Day of Cruising, Annapolis, MD, St Michaels, MD, Day of Cruising, Norfolk, Va, Yorktown / Jamestown, VA, Williamsburg, VA, Mount Vernon, VA, Washington, DC
2027 Sails: Apr 17, May 7, 2028: Nov 1, More...15 Night - Grand Florida Coast & Keys Cruise
Starting in Tampa, FL / St Petersburg FL, Day of Cruising, Punta Gorda, FL, Marco Island, FL, Day of Cruising, Key West, FL, Key Biscayne, FL, West Palm Beach, FL, Cape Canaveral, FL, Day of Cruising, Green Cove Springs, FL, St Augustine, FL, Cruising the Tolomato River, Amelia Island, FL
2027 Sails: Apr 20, 2028: Apr 30, More...
River Cruises sailing on the US East Coast
Click on a cruise ship itinerary sailing on the US East Coast (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just US East Coast), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the US East Coast also sail:
Beaufort River : Hudson River : Patapsco River : Potomac River : Severn River : St Johns River : Tennessee River : Tolomato River : US South Coast
15 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 26, More...
15 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 31, 2027: Nov 8, More...
8 Night - Florida Gulf Coast & Keys CruiseStarting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Nov 3, Nov 10, Nov 17, Nov 24, Dec 1, Dec 8, Dec 15, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Jan 19, Jan 26, Feb 2, Feb 9, Feb 16, Feb 23, Mar 2, Mar 9, Mar 16, Mar 23, Mar 30, Apr 6, Apr 13, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 7, 2027: Mar 19, Apr 2, Apr 16, Apr 30, Nov 8, 2028: Feb 4, Feb 18, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Nov 13, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 9, Feb 23, Nov 25, Dec 9, Dec 23, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Nov 21, Dec 5, Dec 19, 2027: Feb 3, Feb 17, Mar 3, Mar 17, Nov 29, Dec 13, Dec 27, 2028: Feb 16, Mar 1, Dec 2, Dec 16, Dec 30, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, 2028: Mar 8, More...
11 Night - American Revolution CruiseStarting in Washington, DC, Day of Cruising Chesapeake Bay, Norfolk, Va, Day of Cruising, Yorktown / Jamestown, VA, Williamsburg, VA, St Michaels, MD, Annapolis, MD, Day of Cruising Chesapeake Bay and the Delaware River, Philadelphia, Pa
2027 Sails: Apr 7, Apr 27, May 17, More...
11 Night - American Revolution CruiseStarting in Philadelphia, Pa, Day of Cruising, Annapolis, MD, St Michaels, MD, Day of Cruising, Norfolk, Va, Yorktown / Jamestown, VA, Williamsburg, VA, Mount Vernon, VA, Washington, DC
2027 Sails: Apr 17, May 7, 2028: Nov 1, More...
15 Night - Grand Florida Coast & Keys CruiseStarting in Tampa, FL / St Petersburg FL, Day of Cruising, Punta Gorda, FL, Marco Island, FL, Day of Cruising, Key West, FL, Key Biscayne, FL, West Palm Beach, FL, Cape Canaveral, FL, Day of Cruising, Green Cove Springs, FL, St Augustine, FL, Cruising the Tolomato River, Amelia Island, FL
2027 Sails: Apr 20, 2028: Apr 30, More...
