US East Coast Cruises
River Cruises sailing on the US East Coast
River cruises by river name
Cruises on the US East Coast also sail: Beaufort River : Hudson River : Patapsco River : Potomac River : Severn River : Tennessee River : Tolomato River : US South Coast
14 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Nov 5, 2027: Nov 18, 2028: Nov 16, More...
10 Night - American Revolution Cruise
Starting in Washington, DC, Annapolis, MD, St Michaels, MD, Day of Cruising, Norfolk, Va, Williamsburg / Yorktown, VA, Mount Vernon, VA, Washington, DC
2026 Sails: Nov 12, More...
15 Night - Grand Florida Coast & Keys Cruise
Starting in Amelia Island, FL, Day of Cruising, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Day of Cruising, Port Canaveral, FL, West Palm Beach, FL, Key Biscayne, FL, Key West, FL, Day of Cruising, Marco Island, FL, Punta Gorda, FL, St Petersburg FL
2026 Sails: Nov 22, 2027: Nov 2, 2028: Nov 15, More...8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Dec 7, Dec 14, Dec 21, Dec 28, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2027 Sails: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 10, Feb 24, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2027 Sails: Feb 3, Feb 17, Mar 3, Mar 17, Nov 29, Dec 13, Dec 27, 2028: Feb 17, Mar 2, More...
14 Night - Grand Florida Coast & Keys Cruise
Starting in St Petersburg FL, Punta Gorda, FL, Marco Island, FL, Day of Cruising, Key West, FL, Key Biscayne, FL, West Palm Beach, FL, Port Canaveral, FL, Day of Cruising, St Augustine, FL, Cruising the Tolomato River, Amelia Island, FL, Jacksonville, FL
2027 Sails: Feb 3, Apr 21, 2028: May 1, More...14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, More...7 Night - Chesapeake Bay Cruise
Starting in Baltimore, MD, Yorktown, VA, Williamsburg, VA, Cruising the Chesapeake Bay / St Michaels, MD, St Michaels, MD, Annapolis, MD, Baltimore, MD
2027 Sails: May 12, May 19, May 26, Jun 2, More...14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: May 21, More...
River Cruises sailing on the US East Coast
Click on a cruise ship itinerary sailing on the US East Coast (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just US East Coast), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the US East Coast also sail: Beaufort River : Hudson River : Patapsco River : Potomac River : Severn River : Tennessee River : Tolomato River : US South Coast
14 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Nov 5, 2027: Nov 18, 2028: Nov 16, More...
10 Night - American Revolution CruiseStarting in Washington, DC, Annapolis, MD, St Michaels, MD, Day of Cruising, Norfolk, Va, Williamsburg / Yorktown, VA, Mount Vernon, VA, Washington, DC
2026 Sails: Nov 12, More...
15 Night - Grand Florida Coast & Keys CruiseStarting in Amelia Island, FL, Day of Cruising, Amelia Island, FL, Cruising the Tolomato River, St Augustine, FL, Day of Cruising, Port Canaveral, FL, West Palm Beach, FL, Key Biscayne, FL, Key West, FL, Day of Cruising, Marco Island, FL, Punta Gorda, FL, St Petersburg FL
2026 Sails: Nov 22, 2027: Nov 2, 2028: Nov 15, More...
8 Night - Florida Gulf Coast & Keys CruiseStarting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Dec 7, Dec 14, Dec 21, Dec 28, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2027 Sails: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 10, Feb 24, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2027 Sails: Feb 3, Feb 17, Mar 3, Mar 17, Nov 29, Dec 13, Dec 27, 2028: Feb 17, Mar 2, More...
14 Night - Grand Florida Coast & Keys CruiseStarting in St Petersburg FL, Punta Gorda, FL, Marco Island, FL, Day of Cruising, Key West, FL, Key Biscayne, FL, West Palm Beach, FL, Port Canaveral, FL, Day of Cruising, St Augustine, FL, Cruising the Tolomato River, Amelia Island, FL, Jacksonville, FL
2027 Sails: Feb 3, Apr 21, 2028: May 1, More...
14 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, More...
7 Night - Chesapeake Bay CruiseStarting in Baltimore, MD, Yorktown, VA, Williamsburg, VA, Cruising the Chesapeake Bay / St Michaels, MD, St Michaels, MD, Annapolis, MD, Baltimore, MD
2027 Sails: May 12, May 19, May 26, Jun 2, More...
14 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: May 21, More...
