Mississippi River Cruises
River Cruises sailing on the Mississippi River
River cruises by river name
Cruises on the Mississippi River also sail:
Arkansas River : Cumberland River : Lake Barkley : Lake Erie : Licking River : Ohio River : Tennessee River : US South Coast
7 Night - Nashville, Memphis & the Cumberland
Starting in Nashville, Tennessee, Clarksville, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, Scenic Sailing Upper Mississippi, Memphis, Tennessee
2026 Sails: Nov 17, More...7 Night - Mississippi Delta Explorer
Starting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, St Francisville, Louisiana, Baton Rouge, Louisiana, Darrow, Louisiana, New Orleans, Louisiana
2026 Sails: Nov 24, 2027: Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Oct 19, Nov 30, Dec 14, 2028: Feb 1, Feb 15, Feb 29, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, Oct 24, More...7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Oct 12, Oct 26, Nov 23, Dec 7, 2028: Jan 25, Feb 8, Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, More...
7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Dec 12, 2027: Mar 2, Mar 8, Mar 14, Mar 20, Dec 10, Dec 16, 2028: Feb 17, Feb 23, Mar 14, Mar 20, Mar 26, Apr 1, More...7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Dec 15, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 21, Dec 28, More...7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2027 Sails: Jan 19, More...7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2027 Sails: Jan 26, More...14 Night - Bayous, Blues & Bluegrass
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 1, Oct 26, More...22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2027 Sails: Jun 4, 2028: Jun 2, More...7 Night - Mississippi & Ohio River Explorer
Starting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 8, Nov 2, More...
River Cruises sailing on the Mississippi River
Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the Mississippi River also sail:
Arkansas River : Cumberland River : Lake Barkley : Lake Erie : Licking River : Ohio River : Tennessee River : US South Coast
7 Night - Nashville, Memphis & the CumberlandStarting in Nashville, Tennessee, Clarksville, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, Scenic Sailing Upper Mississippi, Memphis, Tennessee
2026 Sails: Nov 17, More...
7 Night - Mississippi Delta ExplorerStarting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, St Francisville, Louisiana, Baton Rouge, Louisiana, Darrow, Louisiana, New Orleans, Louisiana
2026 Sails: Nov 24, 2027: Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Oct 19, Nov 30, Dec 14, 2028: Feb 1, Feb 15, Feb 29, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, Oct 24, More...
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Oct 12, Oct 26, Nov 23, Dec 7, 2028: Jan 25, Feb 8, Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Dec 12, 2027: Mar 2, Mar 8, Mar 14, Mar 20, Dec 10, Dec 16, 2028: Feb 17, Feb 23, Mar 14, Mar 20, Mar 26, Apr 1, More...
7 Night - New Orleans & Southern CharmsStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Dec 15, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 21, Dec 28, More...
7 Night - New Orleans & Southern CharmsStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2027 Sails: Jan 19, More...
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2027 Sails: Jan 26, More...
14 Night - Bayous, Blues & BluegrassStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 1, Oct 26, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2027 Sails: Jun 4, 2028: Jun 2, More...
7 Night - Mississippi & Ohio River ExplorerStarting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 8, Nov 2, More...
