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South Carolina River Cruises

River Cruises that visit North America: United States: South Carolina

River Cruises that depart from South Carolina

See all Cruises that visit South Carolina

Click on a cruise ship itinerary that visits South Carolina (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Carolina), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Beaufort : Charleston : Hilton Head Island


American Cruise Lines, American Legend
American Legend Cruises8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2027 Sails: Feb 3, Feb 17, Mar 3, Mar 17, Nov 29, Dec 13, Dec 27, 2028: Feb 17, Mar 2, More...
American Cruise Lines, American Legend
American Legend Cruises14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, More...
American Cruise Lines, American Eagle
American Eagle Cruises14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: May 21, More...
American Cruise Lines, American Liberty
American Liberty Cruises14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Jun 18, More...
American Cruise Lines, American Legend
American Legend Cruises14 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2027 Sails: Nov 9, More...

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South Carolina River Cruises