Charleston River Cruises
River Cruises that visit North America: United States: South Carolina: Charleston
River Cruises that depart from Charleston
See all Cruises that visit Charleston
River cruises by river name
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2025 Sails: Dec 26, 2026: Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Mar 18, Apr 1, Apr 15, Apr 29, 2027: Mar 19, Apr 2, Apr 16, Apr 30, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...
15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: Mar 28, 2028: Mar 9, More...15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 13, More...15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 22, More...14 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 27, More...14 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Nov 5, 2027: Nov 18, 2028: Nov 16, More...8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2027 Sails: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 10, Feb 24, More...14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, More...14 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: May 21, More...
River Cruises that visit North America: United States: South Carolina: Charleston
River Cruises that depart from Charleston
See all Cruises that visit Charleston
Click on a cruise ship itinerary that visits Charleston (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Charleston), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2025 Sails: Dec 26, 2026: Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Mar 18, Apr 1, Apr 15, Apr 29, 2027: Mar 19, Apr 2, Apr 16, Apr 30, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: Mar 28, 2028: Mar 9, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 13, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 22, More...
14 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 27, More...
14 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Nov 5, 2027: Nov 18, 2028: Nov 16, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2027 Sails: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 10, Feb 24, More...
14 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: Mar 24, More...
14 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2027 Sails: May 21, More...
