South Carolina Cruises
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Related areas: Beaufort : Charleston : Hilton Head Island
8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Apr 10, Nov 24, Dec 8, Dec 22, 2027: Feb 10, Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, Nov 22, Dec 6, 2028: Feb 4, Feb 18, Mar 3, Mar 17, Mar 31, Apr 14, Dec 6, Dec 20, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, More...
8 Night - Southeast Coast & Bahamas
Starting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Grand Bahama Island, Bahamas, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Apr 10, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Apr 15, Apr 29, Nov 7, 2027: Mar 19, Apr 2, Apr 16, Apr 30, Nov 8, 2028: Feb 4, Feb 18, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Nov 13, More...
7 Night - Bermuda-Philadelphia
Starting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Apr 16, Apr 23, Apr 30, May 7, May 14, May 21, May 28, Jun 4, Jun 11, Jun 18, Jun 25, More...
9 Night - Bermuda Beauty to East Coast Elegance
Starting in New York City, New York, Royal Naval Dockyard, Bermuda, Nassau, Bahamas, Charleston, South Carolina, New York City, New York
2026 Sails: Apr 16, More...15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: Apr 17, 2027: Apr 28, 2028: Apr 21, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Apr 17, May 1, May 15, Nov 16, Nov 30, Dec 14, Dec 28, 2027: Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Apr 22, May 6, Oct 31, Nov 14, 2027: Mar 26, Apr 9, Apr 23, May 7, Nov 1, Nov 15, 2028: Jan 28, Feb 11, Feb 25, Mar 10, Mar 24, Apr 7, Apr 21, May 5, Nov 6, Nov 20, More...15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 13, 2027: May 21, 2028: May 20, More...
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Click on a cruise ship itinerary that visits South Carolina (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Carolina), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Beaufort : Charleston : Hilton Head Island
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Apr 10, Nov 24, Dec 8, Dec 22, 2027: Feb 10, Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, Nov 22, Dec 6, 2028: Feb 4, Feb 18, Mar 3, Mar 17, Mar 31, Apr 14, Dec 6, Dec 20, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, More...
8 Night - Southeast Coast & BahamasStarting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Grand Bahama Island, Bahamas, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Apr 10, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Apr 15, Apr 29, Nov 7, 2027: Mar 19, Apr 2, Apr 16, Apr 30, Nov 8, 2028: Feb 4, Feb 18, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Nov 13, More...
7 Night - Bermuda-PhiladelphiaStarting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Apr 16, Apr 23, Apr 30, May 7, May 14, May 21, May 28, Jun 4, Jun 11, Jun 18, Jun 25, More...
9 Night - Bermuda Beauty to East Coast EleganceStarting in New York City, New York, Royal Naval Dockyard, Bermuda, Nassau, Bahamas, Charleston, South Carolina, New York City, New York
2026 Sails: Apr 16, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: Apr 17, 2027: Apr 28, 2028: Apr 21, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Apr 17, May 1, May 15, Nov 16, Nov 30, Dec 14, Dec 28, 2027: Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Apr 22, May 6, Oct 31, Nov 14, 2027: Mar 26, Apr 9, Apr 23, May 7, Nov 1, Nov 15, 2028: Jan 28, Feb 11, Feb 25, Mar 10, Mar 24, Apr 7, Apr 21, May 5, Nov 6, Nov 20, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 13, 2027: May 21, 2028: May 20, More...
