South Carolina Cruises
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Related areas: Beaufort : Charleston : Hilton Head Island
8 Night - Southeast Coast & Bahamas
Starting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Miami, Florida, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Jan 16, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, Aug 20, More...8 Night - Southeast Coast & Bahamas
Starting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Grand Bahama Island, Bahamas, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Feb 5, Mar 5, Mar 13, Apr 10, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Nov 17, Dec 1, Dec 15, Dec 29, 2027: Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, 2028: Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Nov 30, Dec 14, Dec 28, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, Nov 16, Nov 30, Dec 14, Dec 28, 2027: Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Aug 13, Aug 27, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Nov 24, Dec 8, Dec 22, 2027: Feb 10, Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Dec 7, Dec 21, More...8 Night - Southeast Coast & Bahamas
Starting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Miami, Florida, Grand Bahama Island, Bahamas, Baltimore, Maryland
2026 Sails: Feb 13, More...
26 Night - Antilles & Atlantic Gems
Starting in Miami, Oranjestad, Willemstad AN, St Georges, Kingstown, Fort-de-France, Tortola, Miami, Charleston, Norfolk, Royal Naval Dockyard, Freeport, Nassau, Great Stirrup Cay, Miami
2026 Sails: Mar 9, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Mar 18, Apr 1, Apr 15, Apr 29, 2027: Mar 19, Apr 2, Apr 16, Apr 30, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...14 Night - Atlantic & Balmy Bermuda
Starting in Miami, Charleston, Norfolk, Royal Naval Dockyard, Freeport, Nassau, Great Stirrup Cay, Miami
2026 Sails: Mar 21, More...
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Click on a cruise ship itinerary that visits South Carolina (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Carolina), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Beaufort : Charleston : Hilton Head Island
8 Night - Southeast Coast & BahamasStarting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Miami, Florida, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Jan 16, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, Aug 20, More...
8 Night - Southeast Coast & BahamasStarting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Grand Bahama Island, Bahamas, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Feb 5, Mar 5, Mar 13, Apr 10, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Nov 17, Dec 1, Dec 15, Dec 29, 2027: Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, 2028: Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Nov 30, Dec 14, Dec 28, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, Nov 16, Nov 30, Dec 14, Dec 28, 2027: Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Aug 13, Aug 27, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Feb 13, Feb 27, Mar 13, Mar 27, Apr 10, Nov 24, Dec 8, Dec 22, 2027: Feb 10, Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Dec 7, Dec 21, More...
8 Night - Southeast Coast & BahamasStarting in Baltimore, Maryland, Charleston, South Carolina, Orlando (Port Canaveral), Fl, Miami, Florida, Grand Bahama Island, Bahamas, Baltimore, Maryland
2026 Sails: Feb 13, More...
26 Night - Antilles & Atlantic GemsStarting in Miami, Oranjestad, Willemstad AN, St Georges, Kingstown, Fort-de-France, Tortola, Miami, Charleston, Norfolk, Royal Naval Dockyard, Freeport, Nassau, Great Stirrup Cay, Miami
2026 Sails: Mar 9, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Mar 18, Apr 1, Apr 15, Apr 29, 2027: Mar 19, Apr 2, Apr 16, Apr 30, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...
14 Night - Atlantic & Balmy BermudaStarting in Miami, Charleston, Norfolk, Royal Naval Dockyard, Freeport, Nassau, Great Stirrup Cay, Miami
2026 Sails: Mar 21, More...
