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Cape Girardeau River Cruises

River Cruises that visit North America: United States: Missouri: Cape Girardeau

Mississippi River Cruises

Click on a river cruise ship itinerary that visits Cape Girardeau (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just Cape Girardeau), please visit: Cruise Search or try our Virtual Cruise Advisor™.





American Duchess Cruises8 Night - Music of America Cruise from Clarksville to St. Louis
Starting in Clarksville; with stops in Dover, TN; Paducah, KY; Cape Girardeau, MO; Chester, IL; Alton, IL; St. Louis, MO
2020 Sails: Apr 12, More...
American Duchess Cruises8 Night - American Culinary Experience from St. Louis to Cincinnati
Starting in St Louis; with stops in Cape Girardeau; Paducah; Bradenburg; Louisville; Madison
2020 Sails: Apr 19, More...
American Duchess Cruises8 Night - American Music Cruise from Clarksville to Memphis
Starting in Clarksville; with stops in Dover, TN; Paducah, KY; Cape Girardeau, MO; New Madrid, MO; Memphis
2020 Sails: May 10, Sep 20, More...
American Countess Cruises7 Night - American River BBQ Challenge from Memphis to Alton
Starting in Memphis, TN; with stops in New Madrid, MO; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Alton, IL
2020 Sails: May 24, Aug 23, More...
American Duchess Cruises22 Night - The Mighty Mississippi Cruise from New Orleans to Red Wing
Starting in New Orleans; with stops in Nottoway; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; New Madrid, MO; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Alton; Hannibal, MO; Bettendorf, IA; Dubuque, IA; La Crosse, WI; Red Wing, MN
2020 Sails: Jun 21, More...
Queen of the Mississippi Cruises10 Night - Ohio River Cruise from St. Louis to Pittsburgh, PA
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Cincinnati, OH; Maysville, KY; Marietta, OH; Pittsburgh, PA
2020 Sails: Jun 23, Jul 13, Aug 2, 2021: Aug 10, Aug 30, Sep 19, More...
Queen of the Mississippi Cruises10 Night - Ohio River Cruise from Pittsburgh, PA to St. Louis
Starting in Pittsburgh, PA; with stops in Marietta, OH; Maysville, KY; Cincinnati, OH; Louisville, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2020 Sails: Jul 3, Jul 23, Aug 12, 2021: Aug 20, Sep 9, Sep 29, More...
American Harmony Cruises21 Night - Complete Mississippi River Cruise New Orleans, Louisiana to St Paul, Minnesota
Starting in New Orleans, with stops in Oak Alley, Houmas House, Baton Rouge, St Francisville, Natchez, Vicksburg, Greenville, Memphis, New Madrid, Cape Girardeau, Chester, St Louis, Cruising the Mississippi River, Hannibal, River Cruising, Davenport Iowa, Dubuque, Cruising the Mississippi River, La Crosse, Red Wing, St Paul
2020 Sails: Jul 13, More...
American Queen Cruises8 Night - American River BBQ Challenge from Memphis to Alton
Starting in Memphis; with stops in New Madrid, MO; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Alton, IL
2020 Sails: Jul 19, More...
Queen of the Mississippi Cruises7 Night - Cumberland River Cruise from St. Louis to Nashville
Starting in St. Louis, MO; with stops in Chester, IL; Cape Girardeau, MO; Paducah, KY; Dover, TN; Clarksville, TN; Nashville, TN
2020 Sails: Aug 22, Sep 5, Sep 19, More...


Cape Girardeau River Cruises
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