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Cape Girardeau Cruises

Cruises that visit North America: United States: Missouri: Cape Girardeau

See all River Cruises that visit Cape Girardeau

Click on a cruise ship itinerary that visits Cape Girardeau (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cape Girardeau), please visit: Cruise Search or try our Virtual Cruise Advisor™.


American Duchess Cruises8 Night - Special Edition Voyages - Culinary & Cocktails - American Culinary Experience Cruise from Louisville to St. Louis (Alton)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2021 Sails: Jul 4, More...
American Duchess Cruises8 Night - Upper Mississippi River - Midwestern Passage Cruise from Louisville to St. Louis (Alton)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2021 Sails: Jul 4, Sep 26, More...
American Queen Cruises8 Night - Special Edition Voyages - Special Events - Founders Cruise from Louisville to St. Louis (Alton)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2021 Sails: Jul 11, 2022: Aug 14, More...
American Queen Cruises8 Night - Upper Mississippi River - Midwestern Passage Cruise from Louisville to St. Louis (Alton)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2021 Sails: Jul 11, 2022: Aug 14, More...
Queen of the Mississippi Cruises10 Night - Ohio River Cruise from St. Louis to Pittsburgh, PA
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Cincinnati, OH; Maysville, KY; Marietta, OH; Pittsburgh, PA
2021 Sails: Aug 10, Aug 30, Sep 19, 2022: Aug 6, Aug 26, Sep 15, 2023: Aug 5, Aug 25, More...
American Countess Cruises8 Night - Special Edition Voyages - Culinary & Cocktails - American Culinary Experience Cruise from Memphis to St. Louis (Alton)
Starting in Memphis, TN; with stops in New Madrid, MO; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO (Alton)
2021 Sails: Aug 14, More...
Queen of the Mississippi Cruises10 Night - Ohio River Cruise from Pittsburgh, PA to St. Louis
Starting in Pittsburgh, PA; with stops in Marietta, OH; Maysville, KY; Cincinnati, OH; Louisville, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2021 Sails: Aug 20, Sep 9, Sep 29, 2022: Aug 16, Sep 5, Sep 25, 2023: Aug 15, More...
American Duchess Cruises8 Night - Special Edition Voyages - Culinary & Cocktails - American Culinary Experience Cruise from Louisville to Memphis
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; Ashport Landing, TN; Memphis, TN
2021 Sails: Aug 29, More...
American Melody Cruises21 Night - Complete Mississippi River Cruise from New Orleans, LA to St. Paul, MN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2021 Sails: Sep 3, 2022: Jun 10, 2023: Jun 9, More...
American Duchess Cruises8 Night - Special Edition Voyages - Community Outreach River Cruise from Louisville to St. Louis (Alton)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2021 Sails: Sep 26, More...


Cape Girardeau Cruises

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