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Prague River Cruise Departures

River Cruises that depart from Europe: Czech Republic: Prague

River Cruises that visit Prague

See all Cruises that depart from Prague

Vltava River Cruises

Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Prague
Shore Excursions

AmaWaterways Tours, AmaBella Tours
AmaBella Tours10 Night - Christmas Markets On the Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Nov 27, More...
Avalon Waterways Tours, Avalon Illumination Tours
Avalon Illumination Tours9 Night - Christmastime On the Legendary Danube with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Nov 27, More...
Emerald Cruises, Emerald Sky
Emerald Sky10 Night - Classic Prague & Christmas Markets On the Danube
Starting in Prague, Prague / Passau, Passau, Linz, Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Nov 28, More...
Avalon Waterways Tours, Avalon Imagery II Tours
Avalon Imagery II Tours7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Nov 29, More...
Emerald Cruises, Emerald Sun
Emerald Sun17 Night - Prague & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 29, More...
Avalon Waterways Tours, Avalon Visionary Tours
Avalon Visionary Tours8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 2, More...
Avalon Waterways Tours, Avalon Impression Tours
Avalon Impression Tours8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 3, Dec 15, More...
Avalon Waterways Tours, Avalon Panorama Tours
Avalon Panorama Tours9 Night - Christmastime On the Legendary Danube with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways Tours, Avalon Passion Tours
Avalon Passion Tours8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 6, More...
Avalon Waterways Tours, Avalon Tranquility II Tours
Avalon Tranquility II Tours11 Night - Christmastime from Nuremberg to Basel with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 9, More...

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Prague River Cruise Departures