Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 29, More...20 Night - Jewels of Europe with Prague and London
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / London, London
2026 Sails: Aug 29, More...
13 Night - Europe's Rivers & Castles with Prague Pre-Cruise and Paris Post-Cruise
Starting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 30, Oct 25, 2027: Mar 28, May 9, Jul 18, Aug 29, Oct 10, More...
10 Night - Romantic Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Aug 30, Sep 13, Oct 11, 2027: Apr 4, Apr 18, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, More...
10 Night - Romantic Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Sep 2, Sep 16, Sep 30, Oct 14, 2027: Mar 17, Apr 14, Apr 28, May 12, May 26, Jun 9, Jun 23, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, More...
17 Night - Prague & Splendours of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 2, More...
11 Night - Cities of Light
Starting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2026 Sails: Sep 2, Sep 16, Sep 30, Nov 11, Nov 25, 2027: Mar 3, Mar 17, Mar 31, Apr 28, May 12, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, 2028: Mar 1, More...
10 Night - Romantic Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Sep 3, Sep 17, Oct 1, Oct 15, Nov 26, Dec 10, More...
10 Night - Classic Prague & Danube Delights
Starting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Sep 3, Oct 29, More...
10 Night - Romantic Danube (Smithsonian Journeys) with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Sep 4, Oct 2, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 29, More...
20 Night - Jewels of Europe with Prague and LondonStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / London, London
2026 Sails: Aug 29, More...
13 Night - Europe's Rivers & Castles with Prague Pre-Cruise and Paris Post-CruiseStarting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 30, Oct 25, 2027: Mar 28, May 9, Jul 18, Aug 29, Oct 10, More...
10 Night - Romantic Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Aug 30, Sep 13, Oct 11, 2027: Apr 4, Apr 18, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, More...
10 Night - Romantic Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Sep 2, Sep 16, Sep 30, Oct 14, 2027: Mar 17, Apr 14, Apr 28, May 12, May 26, Jun 9, Jun 23, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, More...
17 Night - Prague & Splendours of EuropeStarting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 2, More...
11 Night - Cities of LightStarting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2026 Sails: Sep 2, Sep 16, Sep 30, Nov 11, Nov 25, 2027: Mar 3, Mar 17, Mar 31, Apr 28, May 12, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, 2028: Mar 1, More...
10 Night - Romantic Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Sep 3, Sep 17, Oct 1, Oct 15, Nov 26, Dec 10, More...
10 Night - Classic Prague & Danube DelightsStarting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Sep 3, Oct 29, More...
10 Night - Romantic Danube (Smithsonian Journeys) with Prague Pre-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Sep 4, Oct 2, More...
