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Prague River Cruise Departures

River Cruises that depart from Europe: Czech Republic: Prague

River Cruises that visit Prague

See all Cruises that depart from Prague

Vltava River Cruises

Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Prague
Shore Excursions

Emerald Cruises, Emerald Luna
Emerald Luna20 Night - Prague to Paris & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 21, 2027: Nov 19, More...
Emerald Cruises, Emerald Luna
Emerald Luna17 Night - Prague & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 19, More...
Scenic Luxury, Scenic Jasper
Scenic Jasper17 Night - Christmas Markets with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 20, More...
Scenic Luxury, Scenic Jasper
Scenic Jasper20 Night - Christmas Markets with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 21, 2027: Nov 20, More...
AmaWaterways Tours, AmaReina Tours
AmaReina Tours10 Night - Iconic Christmas Markets with Prague Pre-Cruise
Starting in Prague, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Nov 22, 2027: Dec 12, More...
Scenic Luxury, Scenic Jade
Scenic Jade17 Night - Christmas Markets with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2026 Sails: Nov 22, More...
Scenic Luxury, Scenic Jade
Scenic Jade20 Night - Christmas Markets with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 22, More...
AmaWaterways Tours, AmaSofia Tours
AmaSofia Tours10 Night - Christmas Markets On the Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Nov 26, Dec 10, More...
Emerald Cruises, Emerald Astra
Emerald Astra8 Night - Prague to Budapest & Christmas Time On the Danube
Starting in Prague, Prague / Vienna, Vienna, Bratislava, Budapest
2026 Sails: Nov 26, More...
Emerald Cruises, Emerald Astra
Emerald Astra6 Night - Prague & Christmas Time On the Danube
Starting in Prague, Prague / Vienna, Vienna, Bratislava, Budapest
2026 Sails: Nov 26, More...

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Prague River Cruise Departures