Louisiana River Cruise Departures

River Cruises that depart from North America: United States: Louisiana

River Cruises that visit Louisiana

See all Cruises that depart from Louisiana

Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: New Orleans

21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton), Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2027 Sails: Aug 10, More...

Viking River, Viking Mississippi

14 Night - The Big Easy to the Gateway City
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton)
2027 Sails: Aug 10, More...

American Cruise Lines, American Serenade

7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2028 Sails: May 13, More...

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Louisiana River Cruise Departures