Italy River Cruise Departures
River Cruises that depart from Mediterranean: Italy
River Cruises that visit Italy
See all Cruises that depart from Italy
Italy Coast Cruises
River cruises by river name
Related areas: Lake Como : Milan : Perugia : Rome : Taormina : Venice
14 Night - Grand Tour of the Heart of Italy to Portugal's Douro Valley Cruise
Starting in Perugia, Italy, Umbria, Italy, Spoleto, Italy, Marche, Italy, Orvieto, Italy, Porto, Portugal, Pinhao, Portugal, Castelo Rodrigo, Portugal, Salamanca, Spain, Mateus Palace, Portugal, Lamego, Portugal, Porto, Portugal
2027 Sails: Jul 1, Aug 19, Aug 26, Sep 30, More...
12 Night - Cruise & Rail : a Taste of Italy & Venice
Starting in Taormina, Taormina, Transfer to Train, Ragusa, Palermo, Maratea, Verona, Venice, Venice, Transfer to the Ship, Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice
2027 Sails: Sep 7, More...
11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2027 Sails: Nov 26, Dec 10, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 9, May 23, Jun 6, Jul 4, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, More...
16 Night - Italian Vista with Romantic Rhine and in Lucerne
Starting in Arrive in Rome, Italy, Rome, Rome / Orvieto / Assisi / Perugia, Perugia / Florence / Padua, Padua Excursion to Venice, Padua / Verona / Milan, Milan Excursion to Lake Como, Milan / Lucerne, Switzerland, Lucerne, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 14, Sep 3, More...
14 Night - The Rhine & Moselle W / Lake Como Lucerne -Nb
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Bernkastel, Trier / Excursion to Luxembourg, Cochem, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 19, Jun 21, Jul 11, Jul 30, More...
11 Night - Romantic Rhine with Swiss Alps and Italian Lakes, in Lake Maggiore & in Lucerne (Northbound)
Starting in Lake Maggiore, Italy, Lake Maggiore, Lake Maggiore Excursion to Lake Como, Lake Maggiore / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: Jun 13, Jul 11, Aug 8, Sep 19, Oct 17, More...
14 Night - The Rhine & Moselle W / Lake Como Lucerne -Nb
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Bernkastel, Trier / Excursion to Luxembourg, Cochem, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: Sep 8, More...
11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2028 Sails: Dec 5, More...
11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2028 Sails: Dec 12, More...
River Cruises that depart from Mediterranean: Italy
River Cruises that visit Italy
See all Cruises that depart from Italy
Italy Coast Cruises
Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Lake Como : Milan : Perugia : Rome : Taormina : Venice
14 Night - Grand Tour of the Heart of Italy to Portugal's Douro Valley CruiseStarting in Perugia, Italy, Umbria, Italy, Spoleto, Italy, Marche, Italy, Orvieto, Italy, Porto, Portugal, Pinhao, Portugal, Castelo Rodrigo, Portugal, Salamanca, Spain, Mateus Palace, Portugal, Lamego, Portugal, Porto, Portugal
2027 Sails: Jul 1, Aug 19, Aug 26, Sep 30, More...
12 Night - Cruise & Rail : a Taste of Italy & VeniceStarting in Taormina, Taormina, Transfer to Train, Ragusa, Palermo, Maratea, Verona, Venice, Venice, Transfer to the Ship, Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice
2027 Sails: Sep 7, More...
11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2027 Sails: Nov 26, Dec 10, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 9, May 23, Jun 6, Jul 4, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, More...
16 Night - Italian Vista with Romantic Rhine and in LucerneStarting in Arrive in Rome, Italy, Rome, Rome / Orvieto / Assisi / Perugia, Perugia / Florence / Padua, Padua Excursion to Venice, Padua / Verona / Milan, Milan Excursion to Lake Como, Milan / Lucerne, Switzerland, Lucerne, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 14, Sep 3, More...
14 Night - The Rhine & Moselle W / Lake Como Lucerne -NbStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Bernkastel, Trier / Excursion to Luxembourg, Cochem, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 19, Jun 21, Jul 11, Jul 30, More...
11 Night - Romantic Rhine with Swiss Alps and Italian Lakes, in Lake Maggiore & in Lucerne (Northbound)Starting in Lake Maggiore, Italy, Lake Maggiore, Lake Maggiore Excursion to Lake Como, Lake Maggiore / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: Jun 13, Jul 11, Aug 8, Sep 19, Oct 17, More...
14 Night - The Rhine & Moselle W / Lake Como Lucerne -NbStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Bernkastel, Trier / Excursion to Luxembourg, Cochem, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: Sep 8, More...
11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2028 Sails: Dec 5, More...
11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2028 Sails: Dec 12, More...