San Diego Cruises
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
4 Night - West Coast Getaway with San Diego
Starting in Los Angeles, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Nov 24, More...
5 Night - West Coast Getaway with San Diego
Starting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2026 Sails: Nov 24, More...
18 Night - Panama Canal Cruise : Miami, Cabo Rojo & San Diego
Starting in Miami, Florida, Cabo Rojo, Cartagena CO, Panama Canal (Cruising), Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, San Francisco, California
2026 Sails: Dec 18, More...
14 Night - Mexican Riviera & Baja Peninsula Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Dec 19, More...
18 Night - The Americas & Caribbean
Starting in San Diego, Topolobampo, Loreto, La Paz, Isla Natividad (Sightseeing Only), San Diego, Manzanillo, Puerto Vallarta, Mazatlan, Cabo San Lucas (Baja California Sur), San Diego
2026 Sails: Dec 21, More...
18 Night - Miami to Los Angeles
Starting in Miami, Fl, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, Jalisco, San Diego, California, Los Angeles, California
2026 Sails: Dec 21, More...40 Night - Cruise from Miami to Papeete
Starting in Miami, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, Los Angeles, Nawiliwili, Kahului, Hilo, Honolulu, Nuku Hiva, Rangiroa, Moorea Island, Raiatea, Papeete
2026 Sails: Dec 21, More...14 Night - Mexican Riviera & Baja Peninsula Holiday
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Dec 26, More...
16 Night - Panama Canal & Pacific Gems
Starting in Miami, Cruising the Straits of Florida, George Town, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, San Diego, Los Angeles
2026 Sails: Dec 29, More...24 Night - Mexico Riviera & Circle Hawaii
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Honolulu, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Hilo, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Diego, California
2027 Sails: Jan 2, More...
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
Click on a cruise ship itinerary that visits San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
4 Night - West Coast Getaway with San DiegoStarting in Los Angeles, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Nov 24, More...
5 Night - West Coast Getaway with San DiegoStarting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2026 Sails: Nov 24, More...
18 Night - Panama Canal Cruise : Miami, Cabo Rojo & San DiegoStarting in Miami, Florida, Cabo Rojo, Cartagena CO, Panama Canal (Cruising), Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, San Francisco, California
2026 Sails: Dec 18, More...
14 Night - Mexican Riviera & Baja Peninsula HolidayStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Dec 19, More...
18 Night - The Americas & CaribbeanStarting in San Diego, Topolobampo, Loreto, La Paz, Isla Natividad (Sightseeing Only), San Diego, Manzanillo, Puerto Vallarta, Mazatlan, Cabo San Lucas (Baja California Sur), San Diego
2026 Sails: Dec 21, More...
18 Night - Miami to Los AngelesStarting in Miami, Fl, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, Jalisco, San Diego, California, Los Angeles, California
2026 Sails: Dec 21, More...
40 Night - Cruise from Miami to PapeeteStarting in Miami, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, Los Angeles, Nawiliwili, Kahului, Hilo, Honolulu, Nuku Hiva, Rangiroa, Moorea Island, Raiatea, Papeete
2026 Sails: Dec 21, More...
14 Night - Mexican Riviera & Baja Peninsula HolidayStarting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Dec 26, More...
16 Night - Panama Canal & Pacific GemsStarting in Miami, Cruising the Straits of Florida, George Town, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, San Diego, Los Angeles
2026 Sails: Dec 29, More...
24 Night - Mexico Riviera & Circle HawaiiStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Honolulu, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Hilo, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Diego, California
2027 Sails: Jan 2, More...
