San Diego Cruises
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
11 Night - Mexican Riviera & Pacific Coast
Starting in Vancouver, BC, CA, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Oct 4, More...
5 Night - Socal & Ensenada : Halloween Edition
Starting in Los Angeles, California, Catalina Island, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Oct 24, More...
7 Night - Classic California Coast
Starting in Los Angeles, California, Santa Barbara, California, Ensenada, Mexico, San Diego, California, San Francisco, California, Los Angeles, California
2026 Sails: Nov 1, More...30 Night - Circle Hawaii & Sea of Cortez
Starting in San Diego, California, Hilo, Hawaii, Kona, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California, Cabo San Lucas, Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Nov 19, More...4 Night - West Coast Getaway with San Diego
Starting in Los Angeles, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Nov 24, More...
5 Night - West Coast Getaway with San Diego
Starting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2026 Sails: Nov 24, More...
18 Night - Panama Canal Cruise : Miami, Cabo Rojo & San Diego
Starting in Miami, Florida, Cabo Rojo, Cartagena CO, Panama Canal (Cruising), Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, San Francisco, California
2026 Sails: Dec 18, More...
14 Night - Mexican Riviera & Baja Peninsula Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Dec 19, More...
18 Night - The Americas & Caribbean
Starting in San Diego, Topolobampo, Loreto, La Paz, Isla Natividad (Sightseeing Only), San Diego, Manzanillo, Puerto Vallarta, Mazatlan, Cabo San Lucas (Baja California Sur), San Diego
2026 Sails: Dec 21, More...
18 Night - Miami to Los Angeles
Starting in Miami, Fl, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, Jalisco, San Diego, California, Los Angeles, California
2026 Sails: Dec 21, More...
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
Click on a cruise ship itinerary that visits San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
11 Night - Mexican Riviera & Pacific CoastStarting in Vancouver, BC, CA, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Oct 4, More...
5 Night - Socal & Ensenada : Halloween EditionStarting in Los Angeles, California, Catalina Island, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Oct 24, More...
7 Night - Classic California CoastStarting in Los Angeles, California, Santa Barbara, California, Ensenada, Mexico, San Diego, California, San Francisco, California, Los Angeles, California
2026 Sails: Nov 1, More...
30 Night - Circle Hawaii & Sea of CortezStarting in San Diego, California, Hilo, Hawaii, Kona, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California, Cabo San Lucas, Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Nov 19, More...
4 Night - West Coast Getaway with San DiegoStarting in Los Angeles, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Nov 24, More...
5 Night - West Coast Getaway with San DiegoStarting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2026 Sails: Nov 24, More...
18 Night - Panama Canal Cruise : Miami, Cabo Rojo & San DiegoStarting in Miami, Florida, Cabo Rojo, Cartagena CO, Panama Canal (Cruising), Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, San Francisco, California
2026 Sails: Dec 18, More...
14 Night - Mexican Riviera & Baja Peninsula HolidayStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Dec 19, More...
18 Night - The Americas & CaribbeanStarting in San Diego, Topolobampo, Loreto, La Paz, Isla Natividad (Sightseeing Only), San Diego, Manzanillo, Puerto Vallarta, Mazatlan, Cabo San Lucas (Baja California Sur), San Diego
2026 Sails: Dec 21, More...
18 Night - Miami to Los AngelesStarting in Miami, Fl, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, Jalisco, San Diego, California, Los Angeles, California
2026 Sails: Dec 21, More...
