Rome Cruises
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
14 Night - Mediterranean with Greece, Italy & Croatia
Starting in Civitavecchia (for Rome), Italy, Sarande, Albania, Katakolon (for Olympia), Greece, Valletta, Malta, Sicily (Catania), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy, Corfu, Greece, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2026 Sails: Mar 15, Mar 29, More...
12 Night - Mediterranean Odyssey
Starting in Venice (Fusina), Split, Dubrovnik, Croatia, Corfu (Kerkyra), Sail the Ionian Sea, Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Barcelona
2026 Sails: Mar 16, More...
9 Night - Mediterranean & Greek Isles
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Santorini, Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Athens (Piraeus), Greece
2026 Sails: Mar 19, More...16 Night - Mediterranean with Greece, France & Italy
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Santorini, Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Mar 19, More...
21 Night - Mediterranean & Adriatic Sojourn
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Mar 21, More...14 Night - Mediterranean & Italian Sojourn
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Mar 21, More...
55 Night - Msc World Cruise
Starting in Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Mar 24, More...53 Night - Msc World Cruise
Starting in Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy
2026 Sails: Mar 24, More...
19 Night - An Extended Journey of Sunlit Sophistication & Spectacular Shorelines
Starting in Barcelona, Marseille, Ajaccio (Corsica), Livorno (Florence), Civitavecchia (Rome), Valencia, Palma De Mallorca, Barcelona, Port of Naples, La Valletta, Siracusa (Sicily), Corfu, Kotor, Brindisi, Split, Fusina (Venice)
2026 Sails: Mar 25, More...8 Night - A Journey Through Mediterranean Gems & Historic Grandeur
Starting in Barcelona, Marseille, Ajaccio (Corsica), Livorno (Florence), Civitavecchia (Rome), Valencia, Palma De Mallorca, Barcelona
2026 Sails: Mar 25, More...
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
Click on a cruise ship itinerary that visits Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Mediterranean with Greece, Italy & CroatiaStarting in Civitavecchia (for Rome), Italy, Sarande, Albania, Katakolon (for Olympia), Greece, Valletta, Malta, Sicily (Catania), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy, Corfu, Greece, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2026 Sails: Mar 15, Mar 29, More...
12 Night - Mediterranean OdysseyStarting in Venice (Fusina), Split, Dubrovnik, Croatia, Corfu (Kerkyra), Sail the Ionian Sea, Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Barcelona
2026 Sails: Mar 16, More...
9 Night - Mediterranean & Greek IslesStarting in Barcelona, Spain, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Santorini, Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Athens (Piraeus), Greece
2026 Sails: Mar 19, More...
16 Night - Mediterranean with Greece, France & ItalyStarting in Barcelona, Spain, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Santorini, Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Mar 19, More...
21 Night - Mediterranean & Adriatic SojournStarting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Mar 21, More...
14 Night - Mediterranean & Italian SojournStarting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Mar 21, More...
55 Night - Msc World CruiseStarting in Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Mar 24, More...
53 Night - Msc World CruiseStarting in Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy
2026 Sails: Mar 24, More...
19 Night - An Extended Journey of Sunlit Sophistication & Spectacular ShorelinesStarting in Barcelona, Marseille, Ajaccio (Corsica), Livorno (Florence), Civitavecchia (Rome), Valencia, Palma De Mallorca, Barcelona, Port of Naples, La Valletta, Siracusa (Sicily), Corfu, Kotor, Brindisi, Split, Fusina (Venice)
2026 Sails: Mar 25, More...
8 Night - A Journey Through Mediterranean Gems & Historic GrandeurStarting in Barcelona, Marseille, Ajaccio (Corsica), Livorno (Florence), Civitavecchia (Rome), Valencia, Palma De Mallorca, Barcelona
2026 Sails: Mar 25, More...
