Rome Cruises
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
50 Night - Grand Mediterranean Odyssey
Starting in Fort Lauderdale, Florida, Bermuda, Azores Islands (Ponta Delgada), Portugal, Seville (Cadiz), Spain, Cartagena ES, Mallorca (Palma), Spain, Barcelona, Spain, Corsica (Ajaccio), France, Elba (Portoferraio), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Santorini, Greece, Mykonos, Greece, Athens (Piraeus), Greece, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Dubrovnik, Croatia, Siracusa, Italy, Valletta, Malta, Gibraltar, Casablanca, Morocco (for Marrakesh), Gran Canaria (Las Palmas), Canary Islands, Fort Lauderdale, Florida
2026 Sails: Oct 6, More...25 Night - Spain, Italy and Greece Passage
Starting in Fort Lauderdale, Florida, Bermuda, Azores Islands (Ponta Delgada), Portugal, Seville (Cadiz), Spain, Cartagena ES, Mallorca (Palma), Spain, Barcelona, Spain, Corsica (Ajaccio), France, Elba (Portoferraio), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Santorini, Greece, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Oct 6, More...
21 Night - Mediterranean & Adriatic Sojourn
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Zadar, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Oct 7, More...14 Night - Mediterranean & Italian Sojourn
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Oct 7, More...
7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Italy, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Cagliari, Italy, Palermo (Sicily)
2026 Sails: Oct 8, Oct 15, More...
45 Night - Legendary Ultimate Mediterranean & Atlantic Passage
Starting in New York, Ponta Delgada, Sao Miguel, Azores, Portugal, Lisbon, Portugal, Cruising Strait of Gibraltar, Cartagena ES, Barcelona, Spain, Villefranche-sur-Mer (Nice), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii / Amalfi), Italy, Iraklion (Crete), Greece, Ashdod (Jerusalem), Israel, Haifa (Tel Aviv), Israel, Alexandria EG (Cairo), Egypt, Kusadasi (Ephesus), Turkey, Cruising the Dardanelles, Istanbul, Turkey, Piraeus (Athens), Greece, Valletta, Malta, La Goulette (Tunis), Tunisia, Gibraltar, Cruising Strait of Gibraltar, Cadiz (Seville), Spain, Funchal (Madeira), Portugal, New York
2026 Sails: Oct 8, More...
8 Night - Mediterranean
Starting in Barcelona, Spain, Marseilles (Provence), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Amalfi / Pompeii), Italy, Valletta, Malta, Barcelona, Spain
2026 Sails: Oct 9, More...
10 Night - Italy, France & Malta Cruise
Starting in Barcelona, Spain, Valletta, Malta, Sicily (Messina), Italy, Naples, Italy, Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Barcelona, Spain
2026 Sails: Oct 10, More...
14 Night - Mediterranean with Greece, Italy & Turkey
Starting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Oct 10, 2027: Sep 26, Oct 17, More...21 Night - The Best of the Mediterranean
Starting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Oct 10, More...
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
Click on a cruise ship itinerary that visits Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
50 Night - Grand Mediterranean OdysseyStarting in Fort Lauderdale, Florida, Bermuda, Azores Islands (Ponta Delgada), Portugal, Seville (Cadiz), Spain, Cartagena ES, Mallorca (Palma), Spain, Barcelona, Spain, Corsica (Ajaccio), France, Elba (Portoferraio), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Santorini, Greece, Mykonos, Greece, Athens (Piraeus), Greece, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Dubrovnik, Croatia, Siracusa, Italy, Valletta, Malta, Gibraltar, Casablanca, Morocco (for Marrakesh), Gran Canaria (Las Palmas), Canary Islands, Fort Lauderdale, Florida
2026 Sails: Oct 6, More...
25 Night - Spain, Italy and Greece PassageStarting in Fort Lauderdale, Florida, Bermuda, Azores Islands (Ponta Delgada), Portugal, Seville (Cadiz), Spain, Cartagena ES, Mallorca (Palma), Spain, Barcelona, Spain, Corsica (Ajaccio), France, Elba (Portoferraio), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Santorini, Greece, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Oct 6, More...
21 Night - Mediterranean & Adriatic SojournStarting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Zadar, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Oct 7, More...
14 Night - Mediterranean & Italian SojournStarting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Oct 7, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Italy, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Cagliari, Italy, Palermo (Sicily)
2026 Sails: Oct 8, Oct 15, More...
45 Night - Legendary Ultimate Mediterranean & Atlantic PassageStarting in New York, Ponta Delgada, Sao Miguel, Azores, Portugal, Lisbon, Portugal, Cruising Strait of Gibraltar, Cartagena ES, Barcelona, Spain, Villefranche-sur-Mer (Nice), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii / Amalfi), Italy, Iraklion (Crete), Greece, Ashdod (Jerusalem), Israel, Haifa (Tel Aviv), Israel, Alexandria EG (Cairo), Egypt, Kusadasi (Ephesus), Turkey, Cruising the Dardanelles, Istanbul, Turkey, Piraeus (Athens), Greece, Valletta, Malta, La Goulette (Tunis), Tunisia, Gibraltar, Cruising Strait of Gibraltar, Cadiz (Seville), Spain, Funchal (Madeira), Portugal, New York
2026 Sails: Oct 8, More...
8 Night - MediterraneanStarting in Barcelona, Spain, Marseilles (Provence), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Amalfi / Pompeii), Italy, Valletta, Malta, Barcelona, Spain
2026 Sails: Oct 9, More...
10 Night - Italy, France & Malta CruiseStarting in Barcelona, Spain, Valletta, Malta, Sicily (Messina), Italy, Naples, Italy, Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Barcelona, Spain
2026 Sails: Oct 10, More...
14 Night - Mediterranean with Greece, Italy & TurkeyStarting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Oct 10, 2027: Sep 26, Oct 17, More...
21 Night - The Best of the MediterraneanStarting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Oct 10, More...
