Rome Cruises
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
4 Night - Mediterranean from Naples to Marseille
Starting in Naples, Civitavecchia (Rome), Ajaccio (Corsica), Savona, Marseille
2026 Sails: Sep 17, More...
11 Night - Epicurean Spotlight On Wine
Starting in Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Monte Carlo, Cruising the Ligurian Sea, Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Sep 18, More...
21 Night - The Best of the Mediterranean
Starting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 19, More...14 Night - Mediterranean with Greece, Italy & Turkey
Starting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 19, More...
18 Night - Star Collector : Culture & Charms of Italy & Croatia
Starting in Venice, Rovinj, Split, Kotor, Dubrovnik, Croatia, Giardini Naxos, Sorrento, Rome, Syracuse IT, Italy, Gozo, Valletta, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome
2026 Sails: Sep 19, More...10 Night - Vatican & Croatian Coastlines Cruise Tour
Starting in Venice, Rovinj, Split, Kotor, Dubrovnik, Croatia, Giardini Naxos, Sorrento, Rome
2026 Sails: Sep 19, More...14 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Palma De Mallorca, Malta / La Valletta, Thira (Santorini), Mykonos, Piraeus (Athens), Souda Bay (Crete), Messina (Taormina), Civitavecchia (Rome), Savona
2026 Sails: Sep 20, More...
7 Night - Western Mediterranean from Savona
Starting in Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona
2026 Sails: Sep 20, Sep 27, More...
10 Night - Romantic Mediterranean
Starting in Valletta, Catania (Sicily), Sorrento / Capri, Rome (Civitavecchia), Olbia / Porto Cervo (Sardinia), Portofino, Villefranche, Provence (Marseille), Port-Vendres, Palma De Mallorca, Barcelona
2026 Sails: Sep 20, More...13 Night - Classic Italy - Tour 4A
Starting in Venice, Italy, Florence, Italy, Rome, Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 20, Oct 11, More...
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
Click on a cruise ship itinerary that visits Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
4 Night - Mediterranean from Naples to MarseilleStarting in Naples, Civitavecchia (Rome), Ajaccio (Corsica), Savona, Marseille
2026 Sails: Sep 17, More...
Deal link -> Special
11 Night - Epicurean Spotlight On WineStarting in Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Monte Carlo, Cruising the Ligurian Sea, Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Sep 18, More...
21 Night - The Best of the MediterraneanStarting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 19, More...
14 Night - Mediterranean with Greece, Italy & TurkeyStarting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 19, More...
18 Night - Star Collector : Culture & Charms of Italy & CroatiaStarting in Venice, Rovinj, Split, Kotor, Dubrovnik, Croatia, Giardini Naxos, Sorrento, Rome, Syracuse IT, Italy, Gozo, Valletta, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome
2026 Sails: Sep 19, More...
10 Night - Vatican & Croatian Coastlines Cruise TourStarting in Venice, Rovinj, Split, Kotor, Dubrovnik, Croatia, Giardini Naxos, Sorrento, Rome
2026 Sails: Sep 19, More...
14 Night - Western Mediterranean from SavonaStarting in Savona, Marseille, Barcelona, Palma De Mallorca, Malta / La Valletta, Thira (Santorini), Mykonos, Piraeus (Athens), Souda Bay (Crete), Messina (Taormina), Civitavecchia (Rome), Savona
2026 Sails: Sep 20, More...
7 Night - Western Mediterranean from SavonaStarting in Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona
2026 Sails: Sep 20, Sep 27, More...
Deal link -> Special
10 Night - Romantic MediterraneanStarting in Valletta, Catania (Sicily), Sorrento / Capri, Rome (Civitavecchia), Olbia / Porto Cervo (Sardinia), Portofino, Villefranche, Provence (Marseille), Port-Vendres, Palma De Mallorca, Barcelona
2026 Sails: Sep 20, More...
13 Night - Classic Italy - Tour 4AStarting in Venice, Italy, Florence, Italy, Rome, Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 20, Oct 11, More...
