Rome Cruises
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
28 Night - Mediterranean's Iconic Shores
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice, Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Apr 18, More...
25 Night - Star Collector : Riviera Rhapsody
Starting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona, Palamos, Port Vendres, Sanary-sur-mer, Monte Carlo, Cannes, Portofino, Portoferraio, Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2026 Sails: Apr 18, More...
27 Night - Highlights of Spain - Tour 2C
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, Santa Margherita, Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Apr 19, More...20 Night - Highlights of Spain - Tour 2B
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, Santa Margherita, Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Apr 19, More...
14 Night - Mediterranean & Italian Sojourn
Starting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Apr 20, More...
6 Night - Bcn
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii), Italy, Barcelona, Spain
2026 Sails: Apr 21, More...
7 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy
2026 Sails: Apr 21, Apr 28, May 5, May 12, May 19, May 26, Jun 2, Jun 9, Jun 16, Jun 23, Jun 30, Jul 7, Jul 14, Jul 21, Jul 28, Aug 4, Aug 11, Aug 18, Aug 25, Sep 1, Oct 6, Oct 13, More...
11 Night - Mediterranean Splendor : Amalfi Coast & Ancient Ruins
Starting in Barcelona, Spain, Villefranche-sur-Mer (Nice), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii / Amalfi), Italy, Taormina, Italy, Souda (Chania), Greece, Rhodes, Greece, Kusadasi (Ephesus), Turkey, Piraeus (Athens), Greece
2026 Sails: Apr 22, More...5 Night - Mediterranean
Starting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii), Italy, Barcelona, Spain
2026 Sails: Apr 22, More...7 Night - Mediterranean
Starting in Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2026 Sails: Apr 22, Apr 29, May 6, May 13, May 20, May 27, Jun 3, Jun 10, Jun 17, Jun 24, Jul 1, Jul 8, Jul 15, Jul 22, Jul 29, Aug 5, Aug 12, Aug 19, Aug 26, Sep 2, Oct 7, More...
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
Click on a cruise ship itinerary that visits Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
28 Night - Mediterranean's Iconic ShoresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice, Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Apr 18, More...
25 Night - Star Collector : Riviera RhapsodyStarting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona, Palamos, Port Vendres, Sanary-sur-mer, Monte Carlo, Cannes, Portofino, Portoferraio, Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2026 Sails: Apr 18, More...
27 Night - Highlights of Spain - Tour 2CStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, Santa Margherita, Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Apr 19, More...
20 Night - Highlights of Spain - Tour 2BStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, Santa Margherita, Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Apr 19, More...
14 Night - Mediterranean & Italian SojournStarting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Apr 20, More...
6 Night - BcnStarting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii), Italy, Barcelona, Spain
2026 Sails: Apr 21, More...
7 Night - MediterraneanStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy
2026 Sails: Apr 21, Apr 28, May 5, May 12, May 19, May 26, Jun 2, Jun 9, Jun 16, Jun 23, Jun 30, Jul 7, Jul 14, Jul 21, Jul 28, Aug 4, Aug 11, Aug 18, Aug 25, Sep 1, Oct 6, Oct 13, More...
Deal link -> Special
11 Night - Mediterranean Splendor : Amalfi Coast & Ancient RuinsStarting in Barcelona, Spain, Villefranche-sur-Mer (Nice), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii / Amalfi), Italy, Taormina, Italy, Souda (Chania), Greece, Rhodes, Greece, Kusadasi (Ephesus), Turkey, Piraeus (Athens), Greece
2026 Sails: Apr 22, More...
5 Night - MediterraneanStarting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii), Italy, Barcelona, Spain
2026 Sails: Apr 22, More...
7 Night - MediterraneanStarting in Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2026 Sails: Apr 22, Apr 29, May 6, May 13, May 20, May 27, Jun 3, Jun 10, Jun 17, Jun 24, Jul 1, Jul 8, Jul 15, Jul 22, Jul 29, Aug 5, Aug 12, Aug 19, Aug 26, Sep 2, Oct 7, More...
