Panama City Cruises
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2028 Sails: Jan 14, Feb 15, Apr 19, More...
14 Night - Cartagena to Valparaiso
Starting in Cartagena CO, Panama Canal Transit, Fuerte Amador (Panama City), Manta, Lima (Callao), Valparaiso
2028 Sails: Jan 15, More...
12 Night - Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal
Starting in San Jose, Costa Rica, San Jose, Costa Rica / Puerto Limon, Costa Rica, Puerto Limon, Costa Rica, Bocas Del Toro, Panama, Transit Panama Canal / Panama City, Panama, Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga / Puerto Caldera, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Feb 10, More...
21 Night - Star Collector : Costa Rica, Panama & Aruba
Starting in Puerto Caldera, San Jose, Playa Flamingo, Punta Leona, Quepos, Manuel Antonio National Park, Puerto Jimenez, Golfo Dulce, Isla Partida, Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Gustavia, St Barthelemy, Great Harbour, Jost Van Dyke, Virgin Gorda / Prickly Pear, San Juan
2028 Sails: Feb 21, More...14 Night - Star Collector : Latin America Explorer
Starting in Puerto Caldera, San Jose, Playa Flamingo, Punta Leona, Quepos, Manuel Antonio National Park, Puerto Jimenez, Golfo Dulce, Isla Partida, Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba
2028 Sails: Feb 21, More...18 Night - Discover the Secrets of Costa Rica and Panama
Starting in Puerto Caldera, Costa Rica, Curu and Isla Tortuga, Costa Rica, Quepos, Costa Rica, Golfito, Costa Rica, Isla Cebaco, Panama, Playa del Muerto / Darien National Park, Panama, Pearl Islands, Panama, Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 22, 2029: Feb 22, More...
20 Night - Treasures of the Tropics
Starting in Miami, George Town, Montego Bay, Oranjestad, Willemstad AN, Cartagena CO, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Puerto Limon, Roatan, Santo Tomas, Costa Maya, Mexico, Cozumel, Mexico, Miami
2028 Sails: Mar 5, More...
62 Night - Longitudinal World Cruise VII
Starting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia, Scenic Sailing : Cape Horn, Garibaldi Fjord, Chilean Glaciers, Punta Arenas, Scenic Sailing : Chilean Fjords, Chilean Glaciers, Scenic Sailing : Chilean Fjords, Puerto Chacabuco, Scenic Sailing : Chilean Fjords, Sail the Pacific Ocean, Santiago (Valparaiso), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Panama City (Fuerte Amador), Scenic Sailing : Panama Canal, Sail the Caribbean Sea, Port Antonio, Man of War Bay (Great Inagua), San Salvador Island, Sail the Atlantic Ocean, New York City, New York, Sail the Atlantic Ocean, Halifax, Nova Scotia, Sydney NS, Nova Scotia, Woody Point (Bonne Bay), Newfoundland, Havre-saint-pierre, Quebec, Tadoussac, Quebec, Quebec City, Quebec, Trois-Rivieres, Quebec, Scenic Sailing : St Lawrence Seaway Locks, Toronto, Ontario, Welland Canal, Niagara Falls (Port Colborne), Ontario, Point Pelee, Ontario, Detroit, Michigan, Alpena, Michigan, Mackinac Island, Michigan, Milwaukee, Wisconsin
2028 Sails: Mar 14, More...
62 Night - Longitudinal World Cruise VII
Starting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia, Scenic Sailing : Cape Horn, Garibaldi Fjord, Chilean Glaciers, Punta Arenas, Scenic Sailing : Chilean Fjords, Chilean Glaciers, Scenic Sailing : Chilean Fjords, Puerto Chacabuco, Scenic Sailing : Chilean Fjords, Sail the Pacific Ocean, Santiago (Valparaiso), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Panama City (Fuerte Amador), Scenic Sailing : Panama Canal, Sail the Caribbean Sea, Port Antonio, Man of War Bay (Great Inagua), San Salvador Island, Sail the Atlantic Ocean, New York City, New York, Sail the Atlantic Ocean, Halifax, Nova Scotia, Sydney NS, Nova Scotia, Woody Point (Bonne Bay), Newfoundland, Havre-saint-pierre, Quebec, Tadoussac, Quebec, Quebec City, Quebec, Trois-Rivieres, Quebec, Scenic Sailing : St Lawrence Seaway Locks, Toronto, Ontario, Welland Canal, Niagara Falls (Port Colborne), Ontario, Point Pelee, Ontario, Detroit, Michigan, Alpena, Michigan, Mackinac Island, Michigan, Milwaukee, Wisconsin
2028 Sails: Mar 15, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Port Canaveral (Orlando), Florida, Grand Turk, Turks and Caicos, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2028 Sails: Apr 7, More...
Cruises that visit Central America: Panama: Panama City
Cruises that depart from Panama City
See all River Cruises that visit Panama City
Click on a cruise ship itinerary that visits Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2028 Sails: Jan 14, Feb 15, Apr 19, More...
14 Night - Cartagena to ValparaisoStarting in Cartagena CO, Panama Canal Transit, Fuerte Amador (Panama City), Manta, Lima (Callao), Valparaiso
2028 Sails: Jan 15, More...
12 Night - Costa Rica, Panama from the Pacific to the Atlantic via the Panama CanalStarting in San Jose, Costa Rica, San Jose, Costa Rica / Puerto Limon, Costa Rica, Puerto Limon, Costa Rica, Bocas Del Toro, Panama, Transit Panama Canal / Panama City, Panama, Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga / Puerto Caldera, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Feb 10, More...
21 Night - Star Collector : Costa Rica, Panama & ArubaStarting in Puerto Caldera, San Jose, Playa Flamingo, Punta Leona, Quepos, Manuel Antonio National Park, Puerto Jimenez, Golfo Dulce, Isla Partida, Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Gustavia, St Barthelemy, Great Harbour, Jost Van Dyke, Virgin Gorda / Prickly Pear, San Juan
2028 Sails: Feb 21, More...
14 Night - Star Collector : Latin America ExplorerStarting in Puerto Caldera, San Jose, Playa Flamingo, Punta Leona, Quepos, Manuel Antonio National Park, Puerto Jimenez, Golfo Dulce, Isla Partida, Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba
2028 Sails: Feb 21, More...
18 Night - Discover the Secrets of Costa Rica and PanamaStarting in Puerto Caldera, Costa Rica, Curu and Isla Tortuga, Costa Rica, Quepos, Costa Rica, Golfito, Costa Rica, Isla Cebaco, Panama, Playa del Muerto / Darien National Park, Panama, Pearl Islands, Panama, Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 22, 2029: Feb 22, More...
20 Night - Treasures of the TropicsStarting in Miami, George Town, Montego Bay, Oranjestad, Willemstad AN, Cartagena CO, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Puerto Limon, Roatan, Santo Tomas, Costa Maya, Mexico, Cozumel, Mexico, Miami
2028 Sails: Mar 5, More...
62 Night - Longitudinal World Cruise VIIStarting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia, Scenic Sailing : Cape Horn, Garibaldi Fjord, Chilean Glaciers, Punta Arenas, Scenic Sailing : Chilean Fjords, Chilean Glaciers, Scenic Sailing : Chilean Fjords, Puerto Chacabuco, Scenic Sailing : Chilean Fjords, Sail the Pacific Ocean, Santiago (Valparaiso), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Panama City (Fuerte Amador), Scenic Sailing : Panama Canal, Sail the Caribbean Sea, Port Antonio, Man of War Bay (Great Inagua), San Salvador Island, Sail the Atlantic Ocean, New York City, New York, Sail the Atlantic Ocean, Halifax, Nova Scotia, Sydney NS, Nova Scotia, Woody Point (Bonne Bay), Newfoundland, Havre-saint-pierre, Quebec, Tadoussac, Quebec, Quebec City, Quebec, Trois-Rivieres, Quebec, Scenic Sailing : St Lawrence Seaway Locks, Toronto, Ontario, Welland Canal, Niagara Falls (Port Colborne), Ontario, Point Pelee, Ontario, Detroit, Michigan, Alpena, Michigan, Mackinac Island, Michigan, Milwaukee, Wisconsin
2028 Sails: Mar 14, More...
62 Night - Longitudinal World Cruise VIIStarting in Buenos Aires, Ushuaia, Sail the Drake Passage, Antarctica, Sail the Drake Passage, Scenic Sailing : Cape Horn, Ushuaia, Scenic Sailing : Cape Horn, Garibaldi Fjord, Chilean Glaciers, Punta Arenas, Scenic Sailing : Chilean Fjords, Chilean Glaciers, Scenic Sailing : Chilean Fjords, Puerto Chacabuco, Scenic Sailing : Chilean Fjords, Sail the Pacific Ocean, Santiago (Valparaiso), Sail the Pacific Ocean, Iquique, Sail the Pacific Ocean, Lima (Callao), Sail the Pacific Ocean, Panama City (Fuerte Amador), Scenic Sailing : Panama Canal, Sail the Caribbean Sea, Port Antonio, Man of War Bay (Great Inagua), San Salvador Island, Sail the Atlantic Ocean, New York City, New York, Sail the Atlantic Ocean, Halifax, Nova Scotia, Sydney NS, Nova Scotia, Woody Point (Bonne Bay), Newfoundland, Havre-saint-pierre, Quebec, Tadoussac, Quebec, Quebec City, Quebec, Trois-Rivieres, Quebec, Scenic Sailing : St Lawrence Seaway Locks, Toronto, Ontario, Welland Canal, Niagara Falls (Port Colborne), Ontario, Point Pelee, Ontario, Detroit, Michigan, Alpena, Michigan, Mackinac Island, Michigan, Milwaukee, Wisconsin
2028 Sails: Mar 15, More...
16 Night - Panama Canal - Ocean to OceanStarting in Port Canaveral (Orlando), Florida, Grand Turk, Turks and Caicos, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2028 Sails: Apr 7, More...
