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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Viking Sky Cruises170 Night - Viking World Voyage Iii
Starting in Fort Lauderdale, Florida, Scenic Sailing : Gulf of Mexico, Cozumel, Mexico, Sail the Caribbean Sea, Cartagena CO, Colon, Scenic Sailing : Panama Canal, Sail the Pacific Ocean, Puntarenas (Puerto Caldera), Sail the Pacific Ocean, Cabo San Lucas, Sail the Pacific Ocean, Los Angeles, California, Sail the Pacific Ocean, Oahu (Honolulu), Hawaii, Kona, Hawaii, Sail the Pacific Ocean, Bora Bora (Vaitape), Tahiti (Papeete), Sail the South Pacific Ocean, Rarotonga (Avatiu), Sail the South Pacific Ocean, Wellington, Napier, Rotorua (Tauranga), Auckland, Sail the Tasman Sea, Sydney AU, Sail the Australian Coast, Brisbane, Sail the Australian Coast, Whitsunday Island (Airlie Beach), Cairns, Sail the Coral Sea, Thursday Island, Sail the Arafura Sea, Darwin, Sail the Timor Sea, Komodo National Park (Rinca), Bali (Benoa), Sail the Java Sea, Semarang, Java, Jakarta, Java, Sail the Java Sea, Singapore, Scenic Sailing : Strait of Malacca, Kuala Lumpur (Port Klang), Langkawi, George Town, Phuket, Sail the Bay of Bengal, Colombo, Sail the Laccadive Sea, Male, Sail the Indian Ocean, Victoria SC, Mahe, Seychelles, Sail the Indian Ocean, Mombasa, Zanzibar, Sail the Indian Ocean, Andoany, Nosy-Be, Sail the Indian Ocean, Maputo, Richards Bay, Durban, East London, Gqeberha, Sail the Indian Ocean, Cape Town, Sail the South Atlantic Ocean, Luderitz, Walvis Bay, Sail the South Atlantic Ocean, Luanda, Sail the South Atlantic Ocean, Lagos, Accra (Tema), Takoradi, Sail the Atlantic Ocean, Dakar, Sail the Atlantic Ocean, Sao Vicente Island (Mindelo), Sail the Atlantic Ocean, Santa Cruz de Tenerife, Agadir, Casablanca, Seville (Cadiz), Lisbon, Porto, A Coruna, Sail the Atlantic Ocean, Paris (Honfleur), Dover UK, London (Greenwich), Dover UK, Scenic Sailing : English Channel, Dublin (Dun Laoghaire), Holyhead, Liverpool, Belfast, The Highlands (Ullapool), Orkney Islands (Kirkwall), Edinburgh (Newhaven Harbour), Aberdeen, Shetland Islands (Lerwick), Bergen, Eidfjord, Stavanger, Oslo, Alborg, Copenhagen, Berlin (Warnemunde), Bornholm (Ronne), Gdansk, Sail the Baltic Sea, Tallinn, Stockholm
2026 Sails: Dec 22, More...
Viking Sky Cruises142 Night - Viking World Cruise
Starting in Fort Lauderdale, Florida, Scenic Sailing : Gulf of Mexico, Cozumel, Mexico, Sail the Caribbean Sea, Cartagena CO, Colon, Scenic Sailing : Panama Canal, Sail the Pacific Ocean, Puntarenas (Puerto Caldera), Sail the Pacific Ocean, Cabo San Lucas, Sail the Pacific Ocean, Los Angeles, California, Sail the Pacific Ocean, Oahu (Honolulu), Hawaii, Kona, Hawaii, Sail the Pacific Ocean, Bora Bora (Vaitape), Tahiti (Papeete), Sail the South Pacific Ocean, Rarotonga (Avatiu), Sail the South Pacific Ocean, Wellington, Napier, Rotorua (Tauranga), Auckland, Sail the Tasman Sea, Sydney AU, Sail the Australian Coast, Brisbane, Sail the Australian Coast, Whitsunday Island (Airlie Beach), Cairns, Sail the Coral Sea, Thursday Island, Sail the Arafura Sea, Darwin, Sail the Timor Sea, Komodo National Park (Rinca), Bali (Benoa), Sail the Java Sea, Semarang, Java, Jakarta, Java, Sail the Java Sea, Singapore, Scenic Sailing : Strait of Malacca, Kuala Lumpur (Port Klang), Langkawi, George Town, Phuket, Sail the Bay of Bengal, Colombo, Sail the Laccadive Sea, Male, Sail the Indian Ocean, Victoria SC, Mahe, Seychelles, Sail the Indian Ocean, Mombasa, Zanzibar, Sail the Indian Ocean, Andoany, Nosy-Be, Sail the Indian Ocean, Maputo, Richards Bay, Durban, East London, Gqeberha, Sail the Indian Ocean, Cape Town, Sail the South Atlantic Ocean, Luderitz, Walvis Bay, Sail the South Atlantic Ocean, Luanda, Sail the South Atlantic Ocean, Lagos, Accra (Tema), Takoradi, Sail the Atlantic Ocean, Dakar, Sail the Atlantic Ocean, Sao Vicente Island (Mindelo), Sail the Atlantic Ocean, Santa Cruz de Tenerife, Agadir, Casablanca, Seville (Cadiz), Lisbon, Porto, A Coruna, Sail the Atlantic Ocean, Paris (Honfleur), Dover UK, London (Greenwich)
2026 Sails: Dec 22, More...
HAL Nieuw Amsterdam Cruise Ship21 Night - Panama Canal & Southern Caribbean Holiday
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Dec 27, More...
Viking Mars Cruises14 Night - Panama Canal & Central America
Starting in Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Cartagena CO, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Dec 27, More...
Star Legend Cruise Tours13 Night - Costa Rica, Panama Canal & Machu Picchu Cruise Tour
Starting in Puerto Caldera, Punta Leona, Costa Rica, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon
2026 Sails: Dec 28, More...
Star Legend Cruises8 Night - Costa Rica & Panama Canal
Starting in Puerto Caldera, Punta Leona, Costa Rica, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon
2026 Sails: Dec 28, More...
Seven Seas Grandeur Cruises16 Night - Panama Canal & Pacific Gems
Starting in Miami, Cruising the Straits of Florida, George Town, Cruising the Caribbean Sea, Cartagena CO, Panama Canal Transit, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, San Diego, Los Angeles
2026 Sails: Dec 29, More...
Star Legend Cruise Tours12 Night - Costa Rica, Panama Canal & Machu Picchu Cruise Tour
Starting in Lima, Peru, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Dec 31, 2027: Jan 14, Jan 28, More...
HAL Zuiderdam Cruise Ship14 Night - Panama Canal
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Huatulco, Mexico, Acapulco, Guerrero, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Jan 2, More...
HAL Zaandam Cruise Ship70 Night - Grand South America & Antarctica Voyage
Starting in Fort Lauderdale, Florida, Georgetown, Cayman Islands, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile, Isla Robinson Crusoe, Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Scenic Cruising Glacier Alley, Scenic Cruising Cape Horn, Ushuaia, Argentina, Antarctic, Port Stanley, Falkland Islands, Puerto Madryn, Argentina, Punta Del Este, Uruguay, Montevideo, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil, Abraao, Ilha Grande, Brazil, Rio De Janeiro, Brazil, Salvador da Bahia, Brazil, Recife, Brazil, Fortaleza, Brazil, Icoaraci (Belem), Brazil, Crossing the Equator, Devils Island, French Guiana, Bridgetown, Barbados, Castries, Saint Lucia, Basseterre, St Kitts and Nevis, San Juan, Puerto Rico, Fort Lauderdale, Florida
2027 Sails: Jan 3, More...


Panama Canal Cruises